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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Thioredoxin-related transmembrane protein 2

TMX2, thioredoxin-related transmembrane protein 2
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Top mentioned proteins: CAN, Thioredoxin, fibrillin-1, Prolactin, JAK2
Papers on TMX2
Trichinella spiralis: genome database searches for the presence and immunolocalization of protein disulphide isomerase family members.
Novo et al., Lisbon, Portugal. In J Helminthol, Jan 2016
In addition to a previously described PDI (PDIA2), endoplasmic reticulum protein (ERp57/PDIA3), ERp72/PDIA4, and the molecular chaperones calreticulin (CRT), calnexin (CNX) and immunoglobulin-binding protein/glucose-regulated protein (BIP/GRP78), we identified orthologues of the human thioredoxin-related-transmembrane proteins (TMX1, TMX2 and TMX3) in the genome protein database, as well as ERp44 (PDIA10) and endoplasmic reticulum disulphide reductase (ERdj5/PDIA19).
Src tyrosyl phosphorylates cortactin in response to prolactin.
Diakonova et al., Toledo, United States. In Biochem Biophys Res Commun, Sep 2015
We previously demonstrated that prolactin stimulates invasion of breast cancer cells TMX2-28 through JAK2 and its target serine/threonine kinase PAK1.
SKP2 overexpression is associated with increased serine 10 phosphorylation of p27 (pSer10p27) in triple-negative breast cancer.
Arcaro et al., Amherst Center, United States. In J Cell Physiol, 2014
Use of the triple-negative TMX2-28 breast cancer cell line to address the role of SKP2 in cell cycle progression confirmed that SKP2 contributes to a more rapid cell cycle progression and may regulates pSer10p27 levels.
Identification of UACA, EXOSC9, and ΤΜX2 in bovine periosteal cells by mass spectrometry and immunohistochemistry.
Akiyama, Hirakata, Japan. In Anal Bioanal Chem, 2014
Mass spectrometry analysis of partial peptide data combined with immunohistochemistry also indicated that uveal autoantigen with coiled coil domains and ankyrin repeats (UACA), exosome complex component RRP45 (EXOSC9), and thioredoxin-related transmembrane protein 2 (TMX2) were expressed in bovine periosteal cells.
High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines.
Arcaro et al., Amherst Center, United States. In Epigenetics, 2014
To develop an understanding of Tamoxifen-resistance and identify novel pathways and targets of aberrant methylation, DNA from MCF-7 breast cancer cells and Tamoxifen-resistant derivatives, TMX2-11 and TMX2-28, were analyzed using the Illumina HumanMethylation450 BeadChip.
PAK1 regulates breast cancer cell invasion through secretion of matrix metalloproteinases in response to prolactin and three-dimensional collagen IV.
Diakonova et al., Toledo, United States. In Mol Endocrinol, 2013
In the present study, PRL-activated PAK1 stimulates the invasion of TMX2-28 human breast cancer cells through Matrigel.
The RhoA pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line.
Arcaro et al., Amherst Center, United States. In J Cell Biochem, 2013
We previously demonstrated that the Tamoxifen-selected, MCF-7 derivative, TMX2-28, lacks expression of estrogen receptor α (ERα) and is highly invasive, yet maintains an epithelial morphology.
Palmitoylated TMX and calnexin target to the mitochondria-associated membrane.
Simmen et al., Edmonton, Canada. In Embo J, 2012
TMX2 is enriched on the mitochondria-associated membrane. Targeting TMX to the MAM requires palmitoylation of two membrane-proximal cytosolic cysteines.
PLD1 is overexpressed in an ER-negative MCF-7 cell line variant and a subset of phospho-Akt-negative breast carcinomas.
Arcaro et al., Amherst Center, United States. In Br J Cancer, 2007
We have used a novel variant of the human oestrogen receptor (ER)-positive MCF-7 cell line, TMX2-28, as a model to study breast cancer.
Use of an aggressive MCF-7 cell line variant, TMX2-28, to study cell invasion in breast cancer.
Arcaro et al., Amherst Center, United States. In Mol Cancer Res, 2006
An estrogen receptor-negative variant of the MCF-7 breast cancer cell line, TMX2-28, was used as a model in which to study breast cancer cell invasion.
Identification of cellular membrane proteins interacting with hepatitis B surface antigen using yeast split-ubiquitin system.
Chen et al., Singapore, Singapore. In Int J Med Sci, 2004
These include a resident protein of endoplasmic reticulum (thioredoxin-related transmembrane protein 2), an adaptor protein involved in clathrin-mediated endocytosis and HIV-mediated downregulation of CD4, and a co-receptor of coxsakie B virus.
Phenotypic changes in MCF-7 cells during prolonged exposure to tamoxifen.
Gierthy et al., Albany, United States. In Mol Cell Endocrinol, 2003
In one of two experiments, a heterogeneous cell population emerged (TMX2) that over-expressed estrogen receptor alpha wild type mRNA (ERalpha mRNA) (approximately 20-fold) missing exon 3 (ERDelta3 mRNA) and its corresponding protein (ERDelta3P).
Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2.
Mao et al., Shanghai, China. In Biochem Genet, 2003
molecular cloning and characterization of one member of the thioredoxin superfamily, designated as TMX2; the TMX2 cDNA consists of 1644 nucleotides and contains an open reading frame encoding a protein of 372 amino acids
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