GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Transmembrane protease, serine 5
TMPRSS5, Spinesin
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. [provided by RefSeq, Jul 2008] (from
NCBI)
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Top mentioned proteins:
TMPRSS3, HPN, TMPRSS2, HAD, N-acetyl-beta-D-glucosaminidase
Papers on
TMPRSS5
cAMP-dependent regulation of spinesin/TMPRSS5 gene expression in astrocytes.
GeneRIF
Kyoto, Japan. In J Neurosci Res, 2008
Mouse spinesin is involved in function of astrocytes in spinal cord and there may be astrocyte-specific regulation of its gene expression.
An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss.
Australia. In Hum Mutat, 2008
In addition, TMPRSS2, TMPRSS5, and CORIN, also named TMPRSS10, showed strong likelihood of involvement based on their inner ear expression and mapping position within deafness loci PKSR7, DFNB24, and DFNB25, respectively.
Mosaic serine proteases in the mammalian central nervous system.
Review
Kōchi, Japan. In Front Biosci, 2007
Spinesin/TMPRSS5 is a transmembrane serine protease whose presynaptic distribution on motor neurons in the spinal cord suggests that it is significant for neuronal plasticity.
Molecular cloning and tissue-specific expression analysis of mouse spinesin, a type II transmembrane serine protease 5.
GeneRIF
Kyoto, Japan. In Biochem Biophys Res Commun, 2004
Data report a newly isolated serine protease from mouse CNS, homologous to human spinesin type II transmembrane serine protease 5 and present as a full-length protein as well as type 1, 2, and 3 variants.
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts.
GeneRIF
Loma Linda, United States. In Biochemistry, 2003
The purified IGF-binding protein-5 (IGFBP-5) protease fraction secreted by cultured human osteoblasts has been characterized as ADAM9.
Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord.
Kyoto, Japan. In J Biol Chem, 2002
A cDNA encoding a novel serine protease, which we designated spinesin, has been cloned from human spinal cord.
