Screening of cellular proteins that interact with the classical swine fever virus non-structural protein 5A by yeast two-hybrid analysis.
China. In J Biosci, 2014
Alignment with the NCBI database revealed 16 interactive proteins: DDX5, PSMC3, NAV1, PHF5A, GNB2L1, CSDE1, HSPA8, BRMS1, PPP2R3C, AIP, TMED10, POLR1C, TMEM70, METAP2, CHORDC1 and COPS6.
Assembly of the presenilin γ-/ε-secretase complex.
Toronto, Canada. In J Neurochem, 2012
Several endogenous proteins have been reported to selectively modulate the function of the presenilin complexes; these include transmembrane trafficking protein, 21-KD (TMP21), CD147 antigen (basigin), the γ-secretase-activating protein (gSAP), and the orphan G-protein-coupled receptor 3. Because the structure and assembly of these complexes underlies their activity, this review will discuss current work on the assembly of the complex and on presenilin-interacting proteins that regulate secretase activity.
Transcriptional Regulation of TMP21 by NFAT.
Chongqing, China. In Mol Neurodegener, 2010
BACKGROUND: TMP21 is a member of the p24 cargo protein family, which is involved in protein transport between the Golgi apparatus and ER.