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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

THAP domain containing 5

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Top mentioned proteins: Omi, CAN, V1a, Nba1, PrP
Papers on THAP5
Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination.
Zervos et al., Orlando, United States. In J Mol Cell Cardiol, 2011
Study identified Abro1 as a specific interactor of THAP5, a zinc finger transcription factor that is involved in G2/M control and apoptosis.
THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death.
Zervos et al., Orlando, United States. In Biochem Biophys Res Commun, 2011
this work suggests that THAP5 is a DNA-binding protein and a transcriptional repressor. THAP5 has a pro-apoptotic function and it was induced in melanoma cells under conditions that promoted cell death.
THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.
Zervos et al., Orlando, United States. In Am J Physiol Heart Circ Physiol, 2009
THAP5 and its regulation by Omi/HtrA2 provide a new link between cell cycle control and apoptosis in cardiomyocytes
The CCAAT binding factor can mediate interactions between CONSTANS-like proteins and DNA.
Lifschitz et al., Haifa, Israel. In Plant J, 2006
A mutation in the CCT domain of TCOL1 disrupts the interaction with THAP5 and the analogous mutation in AtCO impairs its function and delays flowering.
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