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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Tubulin folding cofactor B

TBCB, tubulin folding cofactor B, cytoskeleton associated protein 1, Cytoskeleton-associated protein, cytoskeleton-associated protein I, CKAPI
Top mentioned proteins: CAN, alpha-tubulin, TRIC, Ubiquitin, TBC
Papers on TBCB
A quantitative transcriptome reference map of the normal human hippocampus.
Pelleri et al., Bologna, Italy. In Hippocampus, Jan 2016
The tubulin folding cofactor B (TBCB) gene is the best gene at behaving like a housekeeping gene.
The structure of the complex between α-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
Valpuesta et al., Madrid, Spain. In J Cell Sci, Jun 2015
Here, we carried out biochemical assays to dissect the role of the human TBCE and TBCB chaperones in α-tubulin-β-tubulin dissociation.
Cytoskeleton-associated protein 2 is a potential predictive marker for risk of early and extensive recurrence of hepatocellular carcinoma after operative resection.
Miyazaki et al., Chiba, Japan. In Surgery, 2014
RESULTS: Microarray analysis and quantitative reverse transcription-polymerase chain reaction revealed cytoskeleton-associated protein 2 (CKAP2) as a candidate gene associated with early and extensive recurrence of HCC after resection.
Discovery of candidate genes for muscle traits based on GWAS supported by eQTL-analysis.
Wimmers et al., Germany. In Int J Biol Sci, 2013
Most significant SNPs in GL were located on SSC6 and associated with expression levels of PIH1D1, SIGLEC10, TBCB, LOC100518735, KIF1B, LOC100514845, and two unknown genes.
Autoinhibition of TBCB regulates EB1-mediated microtubule dynamics.
Zabala et al., Santander, Spain. In Cell Mol Life Sci, 2013
Among them, TBCB and TBCE are two CAP-Gly domain-containing proteins that together efficiently interact with and dissociate the tubulin dimer.
Tubulin-specific chaperones: components of a molecular machine that assembles the α/β heterodimer.
Cowan et al., New York City, United States. In Methods Cell Biol, 2012
TBCA and TBCB bind to and stabilize newly synthesized quasi-native β- and α-tubulin polypeptides, respectively, following their generation via multiple rounds of ATP-dependent interaction with the cytosolic chaperonin.
CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites.
Camps et al., Bethesda, United States. In Plos One, 2012
Cytoskeleton-associated protein 2, CKAP2, is a microtubule-associated protein that localizes to spindle poles and aids in microtubule stabilization, but the exact function and mechanism of action are poorly understood.
Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150(Glued).
Liebau et al., Ulm, Germany. In Cell Tissue Res, 2012
A yeast-two-hybrid screen for putative interacting proteins of dynactin p150(Glued) has revealed tubulin-folding cofactor B (TBCB).
Antiproliferative factor-induced changes in phosphorylation and palmitoylation of cytoskeleton-associated protein-4 regulate its nuclear translocation and DNA binding.
Planey et al., United States. In Int J Cell Biol, 2011
Cytoskeleton-associated protein 4 (CKAP4) is a reversibly palmitoylated and phosphorylated transmembrane protein that functions as a high-affinity receptor for antiproliferative factor (APF)-a sialoglycopeptide secreted from bladder epithelial cells of patients with interstitial cystitis (IC).
Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway.
Cowan et al., New York City, United States. In Hum Mol Genet, 2010
These include a defective interaction with the chaperone prefoldin, a reduced efficiency in the generation of productive folding intermediates as a result of inefficient interaction with the cytosolic chaperonin, CCT, and, in several cases, a failure to stably interact with TBCB, one of five tubulin-specific chaperones that act downstream of CCT in the tubulin heterodimer assembly pathway.
Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway.
Bomont et al., San Diego, United States. In Hum Mol Genet, 2009
Study demonstrates that, unlike its counterpart TBCE, TBCB only moderately destabilizes microtubules; neither TBCB abundance nor microtubule organization or densities are altered in giant axonal neuropathy mutant fibroblasts.
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Turck et al., São Paulo, Brazil. In Eur Arch Psychiatry Clin Neurosci, 2009
Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
Tubulin cofactor B regulates microtubule densities during microglia transition to the reactive states.
Zabala et al., Santander, Spain. In Exp Cell Res, 2009
TBCB functions as a microtubule density regulator in microglia during activation, and provide an insight into understanding of mechanisms controlling microtubule reorganization during microglial transition between phenotypes.
Capturing protein tails by CAP-Gly domains.
Akhmanova et al., Switzerland. In Trends Biochem Sci, 2008
Cytoskeleton-associated protein-glycine-rich (CAP-Gly) domains are protein-interaction modules implicated in important cellular processes and in hereditary human diseases.
A pachygyria-causing alpha-tubulin mutation results in inefficient cycling with CCT and a deficient interaction with TBCB.
Cowan et al., New York City, United States. In Mol Biol Cell, 2008
Second, there is a failure of CCT-generated folding intermediates to stably interact with TBCB, one of the five tubulin chaperones (TBCA-E) that participate in the pathway leading to the de novo assembly of the tubulin heterodimer.
Dynamic interplay between nitration and phosphorylation of tubulin cofactor B in the control of microtubule dynamics.
Kumar et al., Houston, United States. In Proc Natl Acad Sci U S A, 2008
These findings identified TCoB as the third cytoskeleton protein to be nitrated and suggest a previously undescribed mechanism, whereby growth factor signaling may coordinately integrate nitric oxide signaling in the regulation of microtubule dynamics.
Selective regression of cells expressing mouse cytoskeleton-associated protein 2 transcript by trans-splicing ribozyme.
Lee et al., Seoul, South Korea. In Oligonucleotides, 2006
Cytoskeleton-associated protein 2 (CKAP2) is known to be highly expressed in primary human cancers as well as most cancer cell lines.
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