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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Thymosin beta 10

TB10, thymosin beta 10, TMSB10
Top mentioned proteins: CAN, Actin, ACID, HAD, CD8
Papers on TB10
Multiple Inflammatory Cytokines Converge To Regulate CD8+ T Cell Expansion and Function during Tuberculosis.
Behar et al., Worcester, United States. In J Immunol, Feb 2016
Using retrogenic CD8(+) T cells specific for the M. tuberculosis Ag TB10.4 (EsxH), we observed that IL-12 is the dominant cytokine driving both CD8(+) T cell priming in the lymph node and expansion in the lungs; however, type I IFN and IL-27 have nonredundant roles supporting pulmonary CD8(+) T cell expansion.
A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis.
Behar et al., Worcester, United States. In Plos Pathog, Jan 2016
Despite eliciting a robust memory CD8+ T cell response to the immunodominant Mtb antigen TB10.4 (EsxH), we find the increased frequency of TB10.4-specific
Direct localisation of molecules in tissue sections of growing antler tips using MALDI imaging.
Li et al., Christchurch, New Zealand. In Mol Cell Biochem, Nov 2015
Two protonated molecular ions were selected: m/z 6679 and m/z 6200 corresponding to VEGF and thymosin beta-10, respectively.
The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial.
H4:IC31 Trial Study Groupa et al., Cape Town, South Africa. In Vaccine, Aug 2015
H4:IC31 is an investigational vaccine that contains a fusion protein of the immunodominant antigens TB10.4 and Ag85B, formulated in IC31 adjuvant.
Combined Proteomics and Transcriptomics Identifies Carboxypeptidase B1 and Nuclear Factor κB (NF-κB) Associated Proteins as Putative Biomarkers of Metastasis in Low Grade Breast Cancer.
Nenutil et al., Brno, Czech Republic. In Mol Cell Proteomics, Jul 2015
Increased levels of carboxypeptidase B1 (CPB1), PDZ and LIM domain protein 2 (PDLIM2), and ring finger protein 25 (RNF25) were associated specifically with lymph node positive grade 1 tumors, whereas stathmin 1 (STMN1) and thymosin beta 10 (TMSB10) associated with aggressive tumor phenotype also in high grade tumors at both protein and transcript level.
A double-blind, randomised, placebo-controlled, dose-finding trial of the novel tuberculosis vaccine AERAS-402, an adenovirus-vectored fusion protein, in healthy, BCG-vaccinated infants.
Hatherill et al., Cape Town, South Africa. In Vaccine, Jul 2015
BACKGROUND: Several novel tuberculosis vaccines are currently in clinical trials, including AERAS-402, an adenovector encoding a fusion protein of Mycobacterium tuberculosis antigens 85A, 85B, and TB10.4.
Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.
Behar et al., Worcester, United States. In Plos Pathog, May 2015
Similarly, the murine CD8+ T cell response against M. tuberculosis is dominated by TB10.44-11-specific
The safety and immunogenicity of an adenovirus type 35-vectored TB vaccine in HIV-infected, BCG-vaccinated adults with CD4(+) T cell counts >350 cells/mm(3).
Landry et al., Johannesburg, South Africa. In Vaccine, May 2015
BACKGROUND: The safety and immunogenicity of a replication deficient adenovirus serotype 35 tuberculosis (TB) vaccine containing gene inserts for Antigens (Ag) 85A, Ag85B and TB10.4 (AERAS-402/AD35.TB-S) was evaluated in previously BCG vaccinated, HIV-infected South African adults with baseline CD4 counts >350 cells/mm(3).
Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment.
Maeurer et al., Stockholm, Sweden. In Int J Infect Dis, Mar 2015
We constructed 38 MHC class I multimers covering some of the most frequent MHC class I alleles (HLA-A*02:01, A*24:02, A*30:01, A*30:02, A*68:01, B*58:01, and C*07:01) pertinent to a South African or Zambian population, and presenting the following MTB-derived peptides: the early expressed secreted antigens TB10.4 (Rv0288), Ag85B (Rv1886c), and ESAT-6 (Rv3875), as well as intracellular enzymes, i.e., glycosyltransferase 1 (Rv2957), glycosyltransferase 2 (Rv2958c), and cyclopropane fatty acid synthase (Rv0447c).
Preparation of monoclonal antibodies against Mycobacterium tuberculosis TB10.4 antigen.
Jiao et al., Yangzhou, China. In Monoclon Antib Immunodiagn Immunother, 2014
TB10.4 protein is a member of the ESX family that is necessary for Mycobacterium tuberculosis survival and plays a vital role in mycobacterial pathogenesis.
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Fan et al., Wuhan, China. In Hum Vaccin Immunother, 2014
In order to develop more effective protein subunits depending on the mechanism of cell-mediated immunity against TB, a polyprotein CTT3H, based on 5 immunodominant antigens (CFP10, TB10.4,
Amplification of thymosin beta 10 and AKAP13 genes in metastatic and aggressive papillary thyroid carcinomas.
Puskás et al., Szeged, Hungary. In Pathol Oncol Res, 2012
Amplification of thymosin beta 10 is associated with metastatic and aggressive papillary thyroid carcinomas.
Thymosin beta 10 expression in developing human salivary glands.
Faa et al., Cagliari, Italy. In Early Hum Dev, 2011
The results show, for the first time, a strong expression of thymosin beta 10 in the human salivary glands during the initial phases of the physiological development, present at the 13th week of gestation, and suggesting a role for the peptide in the salivary glands' organogenesis.
Thymosin β10 expression driven by the human TERT promoter induces ovarian cancer-specific apoptosis through ROS production.
Lee et al., Seoul, South Korea. In Plos One, 2011
Thymosin beta10 expression driven by the human TERT promoter induces ovarian cancer-specific apoptosis through ROS production.
Hypomethylation of the thymosin β(10) gene is not associated with its overexpression in non-small cell lung cancer.
Kim et al., Taegu, South Korea. In Mol Cells, 2011
hypomethylation of the promoter is not associated with its overexpression in non-small cell lung cancer
β-Thymosins and interstitial lung disease: study of a scleroderma cohort with a one-year follow-up.
Ferraccioli et al., Roma, Italy. In Respir Res, 2010
Describe beta-thymosins in bronchoalveolar lavage fluid and their possible involvement in the pathogenesis of scleroderma lung disease.
Advances in thymosin beta10 research: differential expression, molecular mechanisms, and clinical implications in cancer and other conditions.
Chen et al., Houston, United States. In Cancer Invest, 2009
Thymosin beta 10 (Tbeta10) is a member of the beta-thymosin family, which has biological activities as an actin-sequestering protein involved in cell motility.
In vivo sampling of extracellular beta-thymosin by ultrafiltration probes.
Huang et al., San Diego, United States. In Ann N Y Acad Sci, 2007
A novel technique using capillary ultrafiltration (CUF) probes linked to mass spectrometry is capable of sensing extracellular thymosin beta-4 and/or thymosin beta-10 in vivo in wounded skin and other tissue microenvironments.
The beta-thymosins, small actin-binding peptides widely expressed in the developing and adult cerebellum.
Anadón et al., Santiago de Compostela, Spain. In Cerebellum, 2002
The most abundant beta-thymosins in mammals are thymosin beta4 (Tbeta4) and thymosin beta10 (Tbeta10), two ubiquitous small (43 amino acids) peptides sharing a high degree of sequence homology.
Small actin-binding proteins: the beta-thymosin family.
Nachmias, Philadelphia, United States. In Curr Opin Cell Biol, 1993
Regulation of the synthesis of thymosin beta 10 and thymosin beta 4 has been found in brain development and after stimulation of several cell types, respectively.
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