gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Family with sequence similarity 19

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] (from NCBI)
Top mentioned proteins: V1a, MT1, MIP
Papers on TAFA-3
Tafa-3 encoding for a secretory peptide is expressed in the mouse pars tuberalis and is affected by melatonin 1 receptor deficiency.
von Gall et al., Frankfurt am Main, Germany. In Gen Comp Endocrinol, 2012
Here we show in mice that the PT expresses Tafa-3 encoding for a secretory peptide.
TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain.
Rupp et al., Sunnyvale, United States. In Genomics, 2004
In H. sapiens, TAFA-3 has two isoforms formed by alternative splicing.
share on facebooktweetadd +1mail to friends