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TAF9B RNA polymerase II, TATA box binding protein

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: POLYMERASE, HAD, Histone, TBP, CAN
Papers on TAF9L
Undibacterium aquatile sp. nov., isolated from a waterfall.
Yi et al., South Korea. In Int J Syst Evol Microbiol, Sep 2015
UNASSIGNED: A Gram-staining-negative, aerobic, motile and rod-shaped strain THG-DN7.3T was isolated from waterfall.
Toward optimal detection of the common prenatal aneuploidies by quantitative fluorescent-polymerase chain reaction: comparison of two commercial assays.
Hume et al., Edmonton, Canada. In Genet Test Mol Biomarkers, 2012
For the sex chromosomes, the difference in the amount of follow-up testing is greater between the assays, as a result of the inclusion in the initial PCR of the TAF9L paralogous marker in the QST*RplusV2 assay.
[Isolation and identification of aerobic denitrifying bacterium Defluvibacter lusatiensis strain DN7 and its heterotrophic nitrification ability].
Chu et al., China. In Ying Yong Sheng Tai Xue Bao, 2012
An aerobic denitrifying bacterium strain DN7 with excellent nitrate removal ability was isolated from the bio-contact oxidation reactor treating bamboo process wastewater.
TAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53.
Bell et al., Sherbrooke, Canada. In Bmc Mol Biol, 2009
Interestingly, gene expression patterns controlled by TAF6delta share similarities with, but are not equivalent to, those reported to change following TAF9 and/or TAF9b depletion.
Dysregulation of X-linked gene expression in Klinefelter's syndrome and association with verbal cognition.
DeLisi et al., Irvine, United States. In Am J Med Genet B Neuropsychiatr Genet, 2007
The 14 X chromosome DEGs were not differentially expressed in prior studies comparing female and male brains suggesting a dysregulation profile unique to KS. Examination of X-linked DEGs, such as GTPBP6, TAF9L, and CXORF21, that show verbal cognition-gene expression correlations may establish a causal link between these genes, neurodevelopment, and language function.
TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.
Tora et al., Strasbourg, France. In Mol Cell Biol, 2005
TAF9b (TAF9L) was identified as a subunit of TFIID.
Altered mouse cholinephosphotransferase gene expression in kidneys of type 2 diabetic KK/TA mouse.
Tomino et al., Tokyo, Japan. In Metabolism, 2004
DN1-3 (Zn-alpha2-glycoprotein, vascular endothelial growth factor receptor [VEGFR]-2, and lactate dehydrogenase [LDH]) were overexpressed and DN7-8 (peroxisome proliferator-activated receptor [PPAR]-interacting protein [PRIP], unknown) were underexpressed in the KK/Ta mouse kidney.
In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.
Manley et al., New York City, United States. In J Biol Chem, 2003
RNA interference experiments suggest that TAF9L is essential for HeLa cell growth and this protein is involved in transcriptional repression.
Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin.
Hanck et al., Chicago, United States. In Insect Biochem Mol Biol, 2000
In insecticidal bioassays the para(74) and para(DN7) fly lines showed greater than 4-fold resistance to allethrin relative to the allethrin sensitive Canton-S control line.
An unusual form of alternative splicing in the HLA-DNA gene.
Long et al., Bethesda, United States. In Immunogenetics, 1990
Two other cDNA clones, DN2 and DN7, revealed an alternative splice that resulted from the use of a splice acceptor upstream of the second exon encoding the alpha 1 domain.
A murine thymocyte clone expressing gamma delta T cell receptor mediates natural killer-like cytolytic function and TH1-like lymphokine production.
Ohno et al., Chiba, Japan. In Cell Immunol, 1990
This line and a representative clone (DN7.12.11) which appear to derive from the minor population of CD3+ DN thymocytes can be stimulated to proliferate and to produce lymphokines by anti-CD3 or anti-Thy-1 antibodies or calcium ionophore plus phorbol ester.
Rearrangement by inversion of a T-cell receptor delta variable region gene located 3' of the delta constant region gene.
Raulet et al., Cambridge, United States. In Proc Natl Acad Sci U S A, 1989
This V delta gene is in the opposite transcriptional polarity to C delta and has rearranged to C delta by inversion in a gamma/delta-expressing hybridoma, DN7.3.
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