Targeting TBP-Associated Factors in Ovarian Cancer.
Providence, United States. In Front Oncol, 2013
At the biochemical level, TAF2 directs TFIID to TATA-less promoters by contact with an Initiator element, which may lead to the deregulation of the transcriptional output of these tumor cells.
Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in 8p11-p12-amplified breast carcinomas.
Göteborg, Sweden. In Oncogenesis, 2013
genomic region (ENPP2, FABP5, IMPAD1, NDRG1, PLEKHF2, RRM2B, SQLE, TAF2, TATDN1, TRPS1, VPS13B).
Microcephaly-thin corpus callosum syndrome maps to 8q23.2-q24.12.
Petah Tikva, Israel. In Pediatr Neurol, 2012
The candidate region includes 22 known or predicted genes, including RAD21, which is related to the cohesion complex EIF3H, which is involved in translation initiation, and TAF2, which may be involved in intellectual disability.