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Syntaxin 6

syntaxin 6
involved in intracellular vesicle trafficking [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, VAMP4, Transferrin, Insulin, ACID
Papers using syntaxin 6 antibodies
Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca2+ signal transduction
Haynes Lee P. et al., In Biochemical and Biophysical Research Communications, 2001
... by permeabilisation with PBT (0.1% triton X-100, 0.3% BSA in PBS), incubation with mouse monoclonal anti-syntaxin 6 antibody (Abcam) and subsequent incubation with ...
Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes.
Gold Jeffrey A., In PLoS ONE, 1997
... Antibodies against SKAP-55, RasGRP1 and Ras were purchased from Transduction Laboratories (San Diego, CA); anti-Syntaxin 6 from BD Biosciences, anti-CD3ε (2C11; hamster anti–mouse ...
Metabolic fate of [14C]-glutamine in mouse cerebral neurons in primary cultures
Chaudhry Farrukh A. et al., In Frontiers in Neuroanatomy, 1983
... Matrigel, anti-syntaxin-6: BD Biosciences, USA ...
Papers on syntaxin 6
Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.
Rentero et al., Barcelona, Spain. In J Biol Chem, Feb 2016
Mechanistically, we found that elevated AnxA6 levels interfered with syntaxin-6 (Stx6)-dependent recycling of integrins to the cell surface.
Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells.
Loh et al., Auckland, New Zealand. In Mol Endocrinol, Jan 2016
In SgIII-reduced cells, POMC accumulated in a compartment that cofractionated and colocalized with syntaxin 6, a marker of the TGN, on sucrose density gradients and in immunocytochemistry, respectively, indicating an accumulation of this protein in the presumed sorting compartment.
Toxoplasma gondii Vps11, a subunit of HOPS and CORVET tethering complexes, is essential for the biogenesis of secretory organelles.
Daher et al., Montpellier, France. In Cell Microbiol, Aug 2015
Recent studies highlighted the essential roles of many regulators such as Rab5A, Rab5C, sortilin-like receptor and syntaxin-6 in secretory organelle biogenesis.
EARP is a multisubunit tethering complex involved in endocytic recycling.
Bonifacino et al., Bethesda, United States. In Nat Cell Biol, May 2015
EARP interacts with the target SNARE syntaxin 6 and various cognate SNAREs.
The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells.
Sørensen et al., Amsterdam, Netherlands. In J Neurosci, 2014
PICK1 colocalized with syntaxin-6, a marker for immature granules.
The SNARE protein vti1a functions in dense-core vesicle biogenesis.
Sørensen et al., Amsterdam, Netherlands. In Embo J, 2014
Here we show that vti1a is absent from mature secretory vesicles in adrenal chromaffin cells, but localizes to a compartment near the trans-Golgi network, partially overlapping with syntaxin-6.
Raft-like membranes from the trans-Golgi network and endosomal compartments.
Waugh, London, United Kingdom. In Nat Protoc, 2013
The isolated subcellular fraction contains less than 1% of the total cellular proteins, but it is highly enriched for syntaxin-6 and Rab11.
Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide.
Klip et al., Toronto, Canada. In Biol Open, 2013
Surface-labeled GLUT4myc that internalized for 30 min accumulated in a Syntaxin-6 (Stx6)- and Stx16-positive perinuclear sub-compartment devoid of furin or internalized transferrin, and displayed insulin-responsive re-exocytosis.
The eukaryotic signal sequence, YGRL, targets the chlamydial inclusion.
Moore et al., United States. In Front Cell Infect Microbiol, 2013
Syntaxin 6, which localizes to the chlamydial inclusion, contains an YGRL signal sequence.
CLN3 loss disturbs membrane microdomain properties and protein transport in brain endothelial cells.
Davidson et al., Bonn, Germany. In J Neurosci, 2013
Here we find that CLN3 is necessary for normal trafficking of the microdomain-associated proteins caveolin-1, syntaxin-6, and multidrug resistance protein 1 (MDR1) in brain endothelial cells.
CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain.
Furuichi et al., Kyoto, Japan. In J Neurosci, 2013
Forebrain-specific Caps1 cKO mice showed reduced immunoreactivity for the DCV marker secretogranin II (SgII) and the trans-Golgi network (TGN) marker syntaxin 6, a reduced number of presynaptic DCVs, and dilated trans-Golgi cisternae in the CA3 region.
Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6.
Choudhury et al., Iowa City, United States. In Biosci Rep, 2012
Recently, the t-SNARE family member, syntaxin-6, has been shown to play an important role in the transport of proteins that are key to diverse cellular dynamic processes.
Syntaxin 6 regulates nerve growth factor-dependent neurite outgrowth.
Mikoshiba et al., Wako, Japan. In Neurosci Lett, 2008
Syntaxin 6 regulates nerve growth factor-dependent neurite outgrowth.
Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface.
Pagano et al., Rochester, United States. In Nat Cell Biol, 2006
Here, we demonstrate that caveolar endocytosis is regulated by syntaxin 6, a target membrane soluble N-ethylmaleimide attachment protein receptor (t-SNARE) involved in membrane fusion events along the secretory pathway.
MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking.
Hirose et al., Yokohama, Japan. In Mol Biol Cell, 2005
Depletion of MARCH-II by small interfering RNA perturbed the TGN localization of syntaxin 6 and TGN38/46
Control of vesicle fusion by a tyrosine phosphatase.
Mustelin et al., Los Angeles, United States. In Nat Cell Biol, 2004
PTP-MEG2 reduced the phosphotyrosine content of NSF and co-localized with NSF and syntaxin 6 in intact cells.
Syntaxin-6 SNARE involvement in secretory and endocytic pathways of cultured pancreatic beta-cells.
Arvan et al., New York City, United States. In Mol Biol Cell, 2004
Syntaxin-6 has a role in secretory and endocytic pathways in pancreatic beta cells
Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.
Gould et al., Glasgow, United Kingdom. In Mol Biol Cell, 2003
syntaxin 6 is involved in a membrane-trafficking step that sequesters Glut4 away from traffic destined for the plasma membrane
Syntaxin 6: the promiscuous behaviour of a SNARE protein.
Tooze et al., London, United Kingdom. In Traffic, 2001
We take, as an example, the promiscuous SNARE syntaxin 6, a SNARE involved in multiple membrane fusion events.
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