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Synaptogyrin 2

This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, Peg3, PRP9, DNA ligase III
Papers on Syngr2
A molecular computational model improves the preoperative diagnosis of thyroid nodules.
Mazzanti et al., Pisa, Italy. In Bmc Cancer, 2011
METHODS: The mRNA expression level of 9 genes (KIT, SYNGR2, C21orf4, Hs.296031, DDI2, CDH1, LSM7, TC1, NATH) was analysed by quantitative PCR (q-PCR) in 93 FNA cytological samples.
Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis.
Byskov et al., Copenhagen, Denmark. In Cell Tissue Res, 2007
The microarray also detected an abundance of vesicle-related genes of which four were upregulated (Syngr2, Stxbp1, Ric-8, SytIX) and one (Myo1c) was downregulated in E13.5 ovaries.
A six-gene model for differentiating benign from malignant thyroid tumors on the basis of gene expression.
Libutti et al., Bethesda, United States. In Surgery, 2005
METHODS: Molecular profiles of benign (follicular adenomas, hyperplastic nodules) and malignant tumors (papillary thyroid carcinomas, follicular variants of papillary thyroid carcinomas) were analyzed using qRT-PCR from our 6-gene model (kit, Hs.296031, Hs.24183, LSM7, SYNGR2, C21orf4).
Molecular hierarchy in neurons differentiated from mouse ES cells containing a single human chromosome 21.
Oshimura et al., Hong Kong, Hong Kong. In Biochem Biophys Res Commun, 2004
Hierarchical clustering patterned specific expression of hChr21 gene dosage effects on neuron outgrowth, migration, and differentiation, such as Syngr2, Dncic2, Eif3sf, and Peg3.
Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.
Kandror et al., Boston, United States. In J Biol Chem, 2003
Cellugyrin and synaptogyrin have roles in facilitating targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment
Characterization of the human synaptogyrin gene family.
Dumanski et al., Stockholm, Sweden. In Hum Genet, 1998
We also characterized two additional members of this novel synaptogyrin gene family in human (SYNGR2 and SYNGR3), and one in mouse (Syngr2).
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