Stathmin 1 in normal and malignant hematopoiesis.
Campinas, Brazil. In Bmb Rep, 2014
Stathmin 1 is a microtubule destabilizer that plays an important role in cell cycle progression, segregation of chromosomes, clonogenicity, cell motility and survival.
Stathmin 1: a novel therapeutic target for anticancer activity.
Carrollton, United States. In Expert Rev Anticancer Ther, 2008
Stathmin 1 (STMN1), also known as p17, p18, p19, 19K, metablastin, oncoprotein 18, LAP 18 and Op18, is a 19 kDa cytosolic protein.
Mitotic chromatin regulates phosphorylation of Stathmin/Op18.
Heidelberg, Germany. In Nature, 1997
It has been shown that Stathmin/Op18 inhibits microtubule polymerization in vitro by interaction with tubulin, and that overexpression in tissue culture cells of non-phosphorylatable mutants of Stathmin/Op18 prevents the assembly of mitotic spindles.