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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Suppression of tumorigenicity 5

ST5, p126
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: pFGE, HAD, ST1, CAN, Suppression of tumorigenicity
Papers on ST5
Dynamics of nasal carriage of methicillin-resistant Staphylococcus aureus among healthcare workers in a tertiary-care hospital in Peru.
Denis et al., Lima, Peru. In Eur J Clin Microbiol Infect Dis, Jan 2016
Multidrug resistant ST5-spa t149-SCCmec I and ST72-spa t148-SCCmec non-typeable were the two most frequent genotypes detected among HCWs (91.7 %, i.e., 22/24 HCW in whom MRSA was isolated in at least one sample) and patients (24/28, 85.7 %).
Molecular Epidemiology of Streptococcus uberis Clinical Mastitis in Dairy Herds: Strain Heterogeneity and Transmission.
Green et al., Nottingham, United Kingdom. In J Clin Microbiol, Jan 2016
Nine STs (ST-5, -6, -20, -22, -24, -35, -233, -361, and -512), eight of which were grouped within a clonal complex (sharing at least four alleles), were statistically overrepresented (OVR STs).
Methicillin-Resistant Staphylococcus aureus in the Community in Luanda, Angola: Blurred Boundaries with the Hospital Setting.
Aires-de-Sousa et al., Lisbon, Portugal. In Microb Drug Resist, Jan 2016
The MRSA isolates mainly belonged to clones A (PFGE type A, spa type t105, ST5-IVa-65%) and B (PFGE B, t3869, ST88-IVa-30%), while MSSA isolates mainly belonged to clone L (PFGE type L, t861, ST508-42%).
Prevalence and Genotype Characterization of Blastocystis hominis Among the Baghmalek People in Southwestern Iran in 2013 - 2014.
Alizadeh et al., Ahvāz, Iran. In Jundishapur J Microbiol, Oct 2015
The Blastocystis subtypes (ST) identified in this study were ST3, ST4, ST5, and ST7 with the most prevalent being ST4 (40.9%).
The association of molecular typing, vancomycin MIC, and clinical outcome for patients with methicillin-resistant Staphylococcus aureus infections.
Shi et al., Taiwan. In J Microbiol Immunol Infect, Oct 2015
isolates with ST239-SCCmecIII, seven (21.9%) isolates with ST5-SCCmecII, six (18.8%) isolates with ST59-SCCmecIV, and two (6.2%) isolates with ST59-SCCmecVT.
Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea.
Hwang et al., Pusan, South Korea. In Mycobiology, Sep 2015
Among the 137 clinical isolates of C. neoformans, the most prevalent genotype was ST5 (n = 131), followed by ST31 (n = 5) and ST127 (n = 1).
Characterization of Staphylococcus aureus from Humans and a Comparison with İsolates of Animal Origin, in North Dakota, United States.
Logue et al., Fargo, United States. In Plos One, 2014
Most of the S. aureus harboring mecA and PVL genes were identified as ST5 and ST8, and exhibited MDR.
Dissemination of fusidic acid resistance among Staphylococcus aureus clinical isolates.
Wang et al., Wenzhou, China. In Bmc Microbiol, 2014
ST5 accounting for 66.1 % (37/56) was the most prevalent ST.
Comparative Prevalence of Immune Evasion Complex Genes Associated with β-Hemolysin Converting Bacteriophages in MRSA ST5 Isolates from Swine, Swine Facilities, Humans with Swine Contact, and Humans with No Swine Contact.
Nicholson et al., Ames, United States. In Plos One, 2014
In the US, a diverse population of LA-MRSA is found including organisms of the ST398, ST9, and ST5 lineages.
Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology.
Singh-Moodley et al., Johannesburg, South Africa. In Plos One, 2014
Based on MLST, the commonest was ST612 clonal complex (CC8) (n = 7) followed by ST5 (CC5) (n = 4), ST36 (CC30) (n = 4) and ST239 (CC8) (n = 3).
Prevalence and Characterization of Staphylococcus aureus in Growing Pigs in the USA.
Davies et al., Saint Paul, United States. In Plos One, 2014
A decade of research of methicillin-resistant S. aureus (MRSA) in pigs shows that the prevalence and predominant genotypes (i.e., ST398, ST9, ST5) of MRSA vary widely geographically, yet knowledge of the epidemiology of S. aureus generally in swine remains rudimentary.
In Vitro Activity of Ceftaroline against Staphylococcus aureus Isolated in 2012 from Asia-Pacific Countries as Part of the AWARE Surveillance Program.
Ambler et al., Schaumburg, United States. In Antimicrob Agents Chemother, 2014
Among the isolates analyzed, sequence type 5 (ST-5) was the most common sequence type encountered; however, all isolates analyzed from Thailand were ST-228.
Clinical outcomes and molecular typing of heterogenous vancomycin-intermediate Staphylococcus aureus bacteremia in patients in intensive care units.
Lu et al., Taiwan. In Bmc Infect Dis, 2014
MLST analysis showed all the isolates in the hVISA group were ST239, while ST239 (14/34; 41.2 %) and ST5 (12/34; 35.3 %) were predominant in the VSSA group (p = 0.007).
New epidemiology of Staphylococcus aureus infection in Asia.
Huang et al., Taiwan. In Clin Microbiol Infect, 2014
Two pandemic HA-MRSA clones, namely multilocus sequence type (ST) 239 and ST5, are disseminated internationally in Asia, whereas the molecular epidemiology of CA-MRSA in Asia is characterized by clonal heterogeneity, similar to that in Europe.
Disruption of ST5 is associated with mental retardation and multiple congenital anomalies.
Rauch et al., Zürich, Switzerland. In J Med Genet, 2010
Using RNA in situ hybridisation in mouse, the authors found that St5 is expressed in the frontal cortex during embryonic development. In adult mouse brain, expression of St5 was especially high in the hippocampal area and cerebellum.
Community-acquired methicillin-resistant Staphylococcus aureus: what do we need to know?
Witte, Wernigerode, Germany. In Clin Microbiol Infect, 2009
ST1, ST5, ST8, and ST22); CA-MRSA ST8 (USA300), which is most frequent in the USA, has meanwhile been reported from Europe.
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