gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

SUMO1/sentrin specific peptidase 6

SspI, Ssp1
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] (from NCBI)
Top mentioned proteins: POLYMERASE, CAN, ACID, HAD, AGE
Papers using SspI antibodies
Turpentine composition of Pinus contorta × Pinus banksiana hybrids and hybrid derivatives
Bousquet Jean et al., In Ecology and Evolution, 1968
... RsaI, HhaI, SspI, HinfI, and MfeI restriction endonucleases (New England BioLabs, Pickering, Ontario, Canada) following ...
Papers on SspI
The Revised Screening Scale for Pedophilic Interests: Predictive and Concurrent Validity.
Freeman et al., Albany, United States. In Sex Abuse, Jan 2016
UNASSIGNED: This study examined the predictive and concurrent validity of the Screening Scale for Pedophilic Interests (SSPI) and its recent revision (SSPI-2), using a large sample of 2,416 sex offenders deemed not to be in need of civil management in New York State.
Detection of Sarcocystis spp. in cattle (Bos taurus) and water buffaloes (Bubalus bubalis) in Iran by PCR-RFLP.
Molayan et al., Ahvāz, Iran. In J Parasit Dis, Dec 2015
PCR products were digested by restricted enzymes (FokI, SspI and DraI).
Accelerated Adipogenic Differentiation of hMSCs in a Microfluidic Shear Stimulation Platform.
Murthy et al., Boston, United States. In Biotechnol Prog, Dec 2015
Additionally, increased fold change for adipogenic markers such as LPL1, CFL1, and SSP1 were observed as a result of shear stimulation.
Bovine Oviduct Epithelial Cells Dedifferentiate Partly in Culture, While Maintaining their Ability to Improve Early Embryo Development Rate and Quality.
Mermillod et al., France. In Reprod Domest Anim, Oct 2015
However, SSP1 and GPX4 transcripts were slightly increased during culture, this rise becoming significant by the end of the culture period.
Discrimination between Mycoplasma mycoides subsp. capri and Mycoplasma capricolum subsp. capricolum using PCR-RFLP and PCR.
Tola et al., Sassari, Italy. In Vet J, Sep 2015
The first primer set LPD-C1-F/LPD-C1-R was used to amplify a 911 bp fragment that was subsequently co-digested with FastDigest PstI, SspI, EcoRI and ClaI enzymes.
Assessment of Apical Expression of Alpha-2 Integrin, Heat Shock Protein, and Proinflammatory and Immunoregulatory Cytokines in Response to Endodontic Infection.
Sobrinho et al., Belo Horizonte, Brazil. In J Endod, Jul 2015
Similarly, the messenger RNA expression of the integrins secreted phosphoprotein 1 (SSP1)/ostepontin and focal adhesion kinase (FAK) decreased in samples from the second collection (P < .05).
The Effect of Polymorphisms in SPP1 on Risk of Fracture: A Case-Control Study.
Tang et al., Beijing, China. In Med Sci Monit, 2014
Hardy-Weinberg equilibrium (HWE) was assessed in the control group based on the genotype distributions of SSP1 poylmorphisms.
Ssp1 CaMKK: A Sensor of Actin Polarization That Controls Mitotic Commitment through Srk1 in Schizosaccharomyces pombe.
Aligue et al., Barcelona, Spain. In Plos One, 2014
The fission yeast Schizosaccharomyces pombe CaMKK, Ssp1, is required for tolerance to limited glucose through the AMPK, Ssp2, and for the integration of cell growth and division through the SAD kinase Cdr2.
Molecular and parasitological study of cryptosporidium isolates from cattle in ilam, west of iran.
Dousti et al., Tabrīz, Iran. In Iran J Parasitol, 2014
A Nested PCR-RFLP protocol amplifying 825 bp fragment of 18s rRNA gene conducted to differentiate species and genotyping of the isolates using SspI and VspI as restriction enzymes.
[Genotypic identification of the bovine leukemia virus].
Alimov et al., In Mol Gen Mikrobiol Virusol, 2013
The strategy VBL PCR-PDRF-genotyping suggested in our work on the basis of 5 restriction endonucleases (PvuII, SspI, HphI, HaeIII, and BstYI) provided correct genotyping identification of the viral pathogen.
Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases.
Sajiki et al., Okinawa, Japan. In Philos Trans R Soc Lond B Biol Sci, 2012
For several mutants of kinases or phosphatases, including CDK, target of rapamycin complex (TORC) 1 and 2, stress-responsive mitogen-activated protein kinase (MAPK) Sty1/Spc1, MAPK kinase Wis1, calcium- and calmodulin-dependent protein kinase kinase-like Ssp1, and type 2A and 2A-related phosphatases inhibitor Sds23, this cell shortening does not normally occur.
Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.
Reverter et al., Barcelona, Spain. In J Biol Chem, 2011
Loop 1 insertion in SENP6 and SENP7 as a platform to discriminate between SUMO1 and SUMO2/3 isoforms in this subclass of the SUMO protease family.
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies.
Hay et al., Dundee, United Kingdom. In Mol Biol Cell, 2011
study of substrate specificity of SENP6; it is also capable of cleaving mixed chains of SUMO-1 and SUMO-2/3; mutation of catalytic cysteine of results in its accumulation in PML NBs; findings indicate SUMO-modified PML is a substrate of SENP6
Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase.
Itzhaki et al., Cambridge, United Kingdom. In J Mol Biol, 2010
The affinity of the subunit Spp1 for modified histone H3 substrates is much higher than that of Swd1 and Swd3.
The SUMO protease SENP6 is essential for inner kinetochore assembly.
Dasso et al., Bethesda, United States. In J Cell Biol, 2010
Results reveal a novel mechanism whereby the finely balanced activities of SENP6 and RNF4 control vertebrate kinetochore assembly through SUMO-targeted destabilization of inner plate components.
Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7.
Reverter et al., New York City, United States. In J Biol Chem, 2008
SENP6 and SENP7 exhibit lower rates for processing pre-SUMO1, pre-SUMO2, or pre-SUMO3 in comparison with SENP2
The morphology and syntax of individuals who use AAC: research review and implications for effective practice.
Light et al., United States. In Augment Altern Commun, 2007
A research review of 31 studies pertaining to the morphology and syntax of individuals who use augmentative and alternative communication (AAC) and who had severe speech and physical impairments (SSPI) was completed.
Molecular detection and differentiation of infectious bursal disease virus.
Lin et al., West Lafayette, United States. In Avian Dis, 2007
One of the approaches has been the use of SspI and NgoM IV restriction enzymes, for restriction endonuclease (RE) analysis of RT-PCR products (RT-PCR-RE) and BstNI and MboI for restriction fragment length polymorphism (RFLP) analysis (RT-PCR-RFLP) to find unique banding patterns associated with antigenic variation within the variable region of the IBDV VP2 protein.
Sporophytic self-incompatibility in Senecio squalidus L (Asteraceae)--the search for S.
Brennan et al., Bristol, United Kingdom. In J Exp Bot, 2003
Stigma-specific proteins associated with the S(1) allele and the S(2) allele have been identified using isoelectric focusing and these proteins have been designated SSP1 (Stigma S-associated Protein 1) and SSP2.
Staphylococcus and biofilms.
Götz, Tübingen, Germany. In Mol Microbiol, 2002
Proteins have been identified that are also involved in biofilm formation, such as the accumulation-associated protein (AAP), the clumping factor A (ClfA), the staphylococcal surface protein (SSP1) and the biofilm-associated protein (Bap).
share on facebooktweetadd +1mail to friends