SGF29 and Sry pathway in hepatocarcinogenesis.
Hamamatsu, Japan. In World J Biol Chem, Sep 2015
Here, we discuss the molecular nature of SFG29 in SPT3-TAF9-GCN5-acetyltransferase complex, a counterpart of yeast SAGA complex, and the mechanism through which the elevated SGF29 expression contribute to oncogenic potential of c-Myc in hepatocellularcarcinoma (HCC).
Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network.
Tokyo, Japan. In Hum Mol Genet, 2012
The spinocerebellar ataxia type 7 (SCA7) gene product, Ataxin-7 (ATXN7), localizes to the nucleus and has been shown to function as a component of the TATA-binding protein-free TAF-containing-SPT3-TAF9-GCN5-acetyltransferase transcription complex, although cytoplasmic localization of ATXN7 in affected neurons of human SCA7 patients has also been detected.