Molecular evolution of the moonlighting protein SMN in metazoans.
Garden City, United States. In Comp Biochem Physiol Part D Genomics Proteomics, 2013
To test this hypothesis, we investigated sequence conservation and dN/dS, which reflects the selection acting on a coding sequence, in SMN and a related protein, splicing factor 30 (SPF30), which is not currently known to be multifunctional.
Tudor domains bind symmetrical dimethylated arginines.
Montréal, Canada. In J Biol Chem, 2005
Herein we show that the Tudor domains of the spinal muscular atrophy gene product SMN, the splicing factor 30 kDa (SPF30), and the Tudor domain-containing 3 (TDRD3) proteins interacted with arginine-glycine-rich motifs in a methylarginine-dependent manner.