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Solute carrier family 38, member 3

mediates glutamine efflux and uptake [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: ACID, fibrillin-1, CAN, HAD, V1a
Papers on sn-1
Phospholipidomic identification of potential serum biomarkers in dengue fever, hepatitis B and hepatitis C using liquid chromatography-electrospray ionization-tandem mass spectrometry.
Shehata et al., Jiddah, Saudi Arabia. In J Chromatogr B Analyt Technol Biomed Life Sci, Feb 2016
The PLs species were characterized on the basis of (i) MS(2) peaks due to polar head, (ii) precursor ion or neutral loss scans, (iii) identification of fatty acid, (iv) identification of sn-1 and sn-2 fatty acid.
Mechanisms and energetics for N-glycosidic bond cleavage of protonated 2'-deoxyguanosine and guanosine.
Rodgers et al., Detroit, United States. In Phys Chem Chem Phys, Feb 2016
UNASSIGNED: Experimental and theoretical investigations suggest that hydrolysis of N-glycosidic bonds generally involves a concerted SN2 or a stepwise SN1 mechanism.
Requirement of phosphoinositides containing stearic acid to control cell polarity.
Bessoule et al., Bordeaux, France. In Mol Cell Biol, Jan 2016
By mass spectrometry, we demonstrated that the proportion of some PIPs with stearic acyl chains were strongly disturbed in a yeast strain (psi1Δ) deficient for the specific incorporation of stearoyl chain at the sn-1 position of PI.
MALDI-TOF MS to monitor the kinetics of phospholipase A2-digestion of oxidized phospholipids.
Schiller et al., Leipzig, Germany. In Methods, Jan 2016
Additionally, investigations on the impact of the position of the unsaturated fatty acyl residue (sn-1 versus sn-2 position) and modifications of the headgroup (for instance phosphatidylcholine (PC) versus phosphatidylethanolamine (PE)) are also lacking.
Ester-crosslink Profiling of the Cutin Polymer of Wild Type and Cutin Synthase Tomato (Solanum lycopersicum L.) Mutants Highlights Different Mechanisms of Polymerization.
Bakan et al., Nantes, France. In Plant Physiol, Jan 2016
Furthermore, in these mutants, esterification of both sn-1,3 and sn-2 positions of glycerol was impacted and their cutin contained a higher molar glycerol to dihydroxyhexadecanoic acid ratio.
Analytical methods for (oxidized) plasmalogens: Methodological aspects and applications.
Fuchs, Leipzig, Germany. In Free Radic Res, May 2015
Plasmalogens are a unique class of glycerophospholipids (GPLs) containing a fatty alcohol linked by a vinyl-ether moiety at the sn-1 position of the glycerol backbone.
Plasmalogens and fatty alcohols in rhizomelic chondrodysplasia punctata and Sjögren-Larsson syndrome.
Brites et al., Porto, Portugal. In J Inherit Metab Dis, 2015
Plasmalogens are a special class of ether-phospholipids, best recognized by their vinyl-ether bond at the sn-1 position of the glycerobackbone and by the observation that their deficiency causes rhizomelic chondrodysplasia punctata (RCDP).
Mechanistic Studies of the Solvolyses of Carbamoyl Chlorides and Related Reactions.
Kevill et al., Dover, United States. In Int J Mol Sci, 2014
Studies of both rate and products are reviewed and the solvolysis reactions are usually SN1, although addition of an amine leads to a superimposable bimolecular component.
Reminiscence of phospholipase B in Penicillium notatum.
Saito, In Proc Jpn Acad Ser B Phys Biol Sci, 2013
We purified the PLB in Penicillium notatum and showed that it catalyzed deacylation of sn-1 and sn-2 fatty acids of 1,2-diacylphospholipids and also sn-1 or sn-2 fatty acids of 1- or 2-monoacylphospholipids (lysophospholipids).
Plant phospholipase A: advances in molecular biology, biochemistry, and cellular function.
Weselake et al., In Biomol Concepts, 2013
Plant PLAs can be grouped into three families, PLA1, PLA2, and patatin-like PLA, that catalyze the hydrolysis of acyl groups from the sn-1 and/or sn-2 position.
Occurrence of multiple subsequent neoplasms in long-term survivors of childhood cancer: a report from the childhood cancer survivor study.
Robison et al., Memphis, United States. In J Clin Oncol, 2011
Those surviving the first SN (SN1) remain at risk to develop multiple SNs.
Differential axial localization along the mouse brain vascular tree of luminal sodium-dependent glutamine transporters Snat1 and Snat3.
Verrey et al., Zürich, Switzerland. In J Cereb Blood Flow Metab, 2011
In this study, the in vivo endothelial membrane localization of the sodium-dependent glutamine transporters Snat3 (Slc38a3) and Snat1 (Slc38a1) was investigated in the mouse brain microvasculature.
Changes of plasma glutamine concentration and hepatocyte membrane system N transporters expression in early endotoxemia.
Li et al., Nanjing, China. In J Surg Res, 2011
The effect of lipopolysaccharides on system N expression occurs not only at the protein level, but also at the mRNA level
Manganese-induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin-mediated proteolytic system.
Aschner et al., Nashville, United States. In Glia, 2010
Mn(2+)-induced SNAT3 protein degradation and the dysregulation of Gln homeostasis in primary astrocyte cultures proceeds through the ubiquitin-mediated proteolytic system
Rapid downregulation of the rat glutamine transporter SNAT3 by a caveolin-dependent trafficking mechanism in Xenopus laevis oocytes.
Bröer et al., Canberra, Australia. In Am J Physiol Cell Physiol, 2010
Data report that the transport activity of the glutamine transporter SNAT3 is rapidly reduced on PKC activation by phorbol esters via a specific trafficking mechanism in oocytes.
Regulation of DNA Topoisomerase IIbeta through RNA-dependent association with heterogeneous nuclear ribonucleoprotein U (hnRNP U).
Tsutsui et al., Okayama, Japan. In J Biol Chem, 2010
hnRNP U/SAF-A/SP120 regulates the enzyme DNA Topoisomerase IIbeta in dual ways
Dynamic processes leading to covalent bond formation for S(N)1 reactions.
Peters, Boulder, United States. In Acc Chem Res, 2007
The SN1 reaction mechanism is one of the most fundamental processes in organic chemistry.
Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission.
Edwards et al., San Francisco, United States. In Cell, 2000
Using intracellular pH measurements, we have now identified an orphan protein related to a vesicular neurotransmitter transporter as system N. Functional analysis shows that this protein (SN1) involves H+ exchange as well as Na+ cotransport and, under physiological conditions, mediates glutamine efflux as well as uptake.
Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis.
Michell et al., Birmingham, United Kingdom. In Nature, 1997
Two widespread eukaryotic phosphoinositide-based signal transduction mechanisms, phosphoinositidase C-catalysed phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P2) hydrolysis and 3-OH kinase-catalysed PtdIns(4,5)P2 phosphorylation, make the second messengers inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) sn-1,2-diacylglycerol and PtdIns(3,4,5)P3.
Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway.
Hofschneider et al., Martinsried, Germany. In Nature, 1993
An increase in the endogenous protein kinase C (PKC) activator sn-1,2-diacylglycerol and the subsequent activation of PKC give rise to activation of the transcription factor AP-1 (Jun-Fos).
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