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Solute carrier family 25, member 32

Folate metabolism is distributed between the cytosolic and mitochondrial compartments. SLC25A32 is a transporter that shuttles folates from the cytoplasm into mitochondria (Titus and Moran, 2000 [PubMed 10978331]).[supplied by OMIM, Mar 2008] (from NCBI)
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Top mentioned proteins: methylenetetrahydrofolate reductase, AGE, HAD, ACID, BHMT
Papers on SLC25A32
Regulatory variant in FZD6 gene contributes to nonsyndromic cleft lip and palate in an African-American family.
Hecht et al., Houston, United States. In Mol Genet Genomic Med, Sep 2015
This region contained four genes, Frizzled-6 (FZD6), Matrilin-2 (MATN2), Odd-skipped related 2 (OSR2) and Solute Carrier Family 25, Member 32 (SLC25A32).
Development of [(11)C]MFTC for PET imaging of fatty acid amide hydrolase in rat and monkey brains.
Zhang et al., Chiba, Japan. In Acs Chem Neurosci, Mar 2015
Pretreatment with MFTC or FAAH-selective URB597 significantly reduced the uptake in the brain.
Polymorphism of SLC25A32, the folate transporter gene, is associated with plasma folate levels and bone fractures in Japanese postmenopausal women.
Inoue et al., Tokyo, Japan. In Geriatr Gerontol Int, 2014
We speculated that the SLC25A32 gene, the mitochondrial inner membrane folate transporter, also could be implicated in the regulation of folate metabolism and fracture.
Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males.
Cassano et al., Ithaca, United States. In J Nutr, 2012
A gene × folate interaction (MAT2B) and 2 gene × vitamin B-12 interactions (BHMT, SLC25A32) reached the FDR P-adjusted ≤2.00 × 10(-1) threshold.
Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability.
Leeder et al., Kansas City, United States. In Pharmacogenet Genomics, 2012
In univariate analyses, clinical variables including sex, age, and folate supplementation in addition to variations in MTHFR, MTR, and SLC25A32 were associated with differential intracellular folate redox concentrations.
Effect of chronic alcohol exposure on folate uptake by liver mitochondria.
Said et al., Long Beach, United States. In Am J Physiol Cell Physiol, 2012
Transport of folate from the cytoplasm into the mitochondria is via a specific carrier-mediated process involving the mitochondrial folate transporter (MFT).
Tetrahydrofolate recognition by the mitochondrial folate transporter.
Moran et al., Richmond, United States. In J Biol Chem, 2011
identified residues in the walls and at the base of the transport cavity that are involved in substrate recognition by the MFT
Mitochondrial fatty acid transport enzyme deficiency--implications for in vitro fertilization.
Feil et al., Adelaide, Australia. In Fertil Steril, 2009
Patient with SLC25A32 deficiency was able to have a successful pregnancy after fertilization in vitro.
Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system.
Fredriksson et al., Uppsala, Sweden. In Genomics, 2006
These were provided with following gene symbols by the HGNC: SLC25A32, SLC25A33, SLC25A34, SLC25A35, SLC25A37, SLC25A38, SLC25A39, SLC25A40, SLC25A41, SLC25A42, SLC25A43, SLC25A44, SLC25A45, and SLC25A46.
Attentional load of the primary task influences the frontal but not the temporal generators of mismatch negativity.
Valeriani et al., Roma, Italy. In Brain Res Cogn Brain Res, 2005
We recorded event-related potentials (ERPs) in nine healthy subjects while reading and during a demanding visual task (Multiple Features Target Cancellation, MFTC).
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