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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Septin 10

SEPT10, Septin-10
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Lipoprotein Lipase, Actin, SEPT9, ZAP-70, cdc10
Papers on SEPT10
Surrogate molecular markers for IGHV mutational status in chronic lymphocytic leukemia for predicting time to first treatment.
Neri et al., Cosenza, Italy. In Leuk Res, Aug 2015
Two (SNORA70F, NRIP1) of the down-regulated and 6 (SEPT10, ZNF667, TGFBR3, MBOAT1, LPL, CRY1) of the up-regulated genes were significantly associated with a reduced risk of disease progression in both sets.
Possible role of a septin, SEPT1, in spreading in squamous cell carcinoma DJM-1 cells.
Nagata et al., Gifu, Japan. In Biol Chem, 2013
In immunoprecipitation assays, SEPT1 and SEPT5 were found to form a complex in DJM-1 cells, whereas SEPT9, SEPT11 and SEPT14 formed a distinct complex with other septins including SEPT7, SEPT8 and SEPT10, in which SEPT5 was not included.
Septins of Platyhelminths: identification, phylogeny, expression and localization among developmental stages of Schistosoma mansoni.
Brindley et al., São Carlos, Brazil. In Plos Negl Trop Dis, 2012
These orthologues were related to the SEPT5, SEPT10 and SEPT7 septins of humans, and hence we have termed the schistosome septins SmSEPT5, SmSEPT10, SmSEPT7.1 and SmSEPT7.2.
Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen.
Kuroda et al., United States. In Cancer Sci, 2012
we found that paclitaxel-resistant tumors had decreased expression of SEPT10.
Linking the septin expression with carcinogenesis.
Yu et al., Shanghai, China. In Mol Biol Rep, 2010
Significantly, SEPT2, SEPT8, SEPT9, SEPT11 were consistently up-regulated, and SEPT4, SEPT10 were down-regulated in most cancer types investigated.
Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia.
Stilgenbauer et al., Ulm, Germany. In Haematologica, 2010
With regards to overall survival, expression of ATM, ADAM29, TCL1, and SEPT10 provided prognostic information in addition to that derived from clinical and genetic factors.
Are surrogates of IGHV gene mutational status useful in B-cell chronic lymphocytic leukemia? The example of Septin-10.
Gattei et al., In Leukemia, 2008
Lack of SEPT10 transcript is associated with B-cell chronic lymphocytic leukemia
Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin.
Petty et al., Ann Arbor, United States. In Mamm Genome, 2007
SEPT14 shares closest homology to SEPT10, a human dendritic septin, and limited homology to SEPT9 isoforms.
Deregulated expression of fat and muscle genes in B-cell chronic lymphocytic leukemia with high lipoprotein lipase expression.
German CLL Study Group et al., Vienna, Austria. In Leukemia, 2006
Of these, the top three genes associated with time to first treatment were Septin10, DMD and Gravin (P</=0.01).
The predictive value of lipoprotein lipase for survival in chronic lymphocytic leukemia.
Valk et al., Rotterdam, Netherlands. In Haematologica, 2006
RESULTS: The selected genes, i.e., ZAP70, LPL, SPG20, ADAM29, NRIP1, AKAP12, DMD, SEPT10, TPM2 and CLECSF2, showed prognostic significance.
Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells.
Cao et al., Shanghai, China. In Biochem Biophys Res Commun, 2003
Cloning and functional characterization of septin 10.
Mammalian septins nomenclature.
Zieger et al., Charlottesville, United States. In Mol Biol Cell, 2002
The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively.
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