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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Septin 3

SEP3, septin 3, AGL9, SEPT3
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: selenoprotein P, MEN, SEP2, Phosphodiesterase, PDE5
Papers using SEP3 antibodies
Functional divergence within the APETALA3/PISTILLATA floral homeotic gene lineages
Angenent Gerco C et al., In BMC Plant Biology, 2002
... SEP3 expression analysis in transgenic Arabidopsis plants ...
Papers on SEP3
Efficacy and safety of phosphodiesterase type 5 (PDE5) inhibitors in treating erectile dysfunction after bilateral nerve-sparing radical prostatectomy.
Gao et al., Yantai, China. In Andrologia, Feb 2016
P < 0.00001]; and successful intercourse (SEP3) (OR = 47, 95%CI = 3-13.98,
Evolution of DNA-Binding Sites of a Floral Master Regulatory Transcription Factor.
Kaufmann et al., Wageningen, Netherlands. In Mol Biol Evol, Jan 2016
Here, we performed comparative ChIP (chromatin immunoprecipitation)-seq experiments of the MADS-domain transcription factor SEPALLATA3 (SEP3) in two closely related Arabidopsis species: Arabidopsis thaliana and A. lyrata which have very similar floral organ morphology.
Briassoulis et al., Vienna, Austria. In Shock, Oct 2015
INTRODUCTION: Systemic inflammation is associated with an excessive production of nitric oxide (NO), which interferes with a number of metabolic pathways, including mitochondrial ATP synthesis.
Imaging early stages of the female reproductive structure of arabidopsis by confocal laser scanning microscopy.
de Folter et al., Irapuato, Mexico. In Dev Dyn, Oct 2015
We demonstrate the applicability using a cytokinin response marker (TCS::GFP), an auxin response marker (DR5::VENUS), and a SEPALLATA3 marker (SEP3::SEP3:GFP).
Structural and Thermodynamic Properties of Septin 3 Investigated by Small-Angle X-Ray Scattering.
Itri et al., Ancona, Italy. In Biophys J, Jul 2015
In this work, we have investigated by in-solution small-angle x-ray scattering the structural and thermodynamic properties of a human septin 3 construct, SEPT3-GC, which contains both of both interfaces (G and NC) responsible for septin-septin interactions.
[Efficacy and safety of phosphodiesterase inhibitors for erectile dysfunction in diabetic men: A meta analysis].
Wu et al., In Zhonghua Nan Ke Xue, May 2015
FEM analysis of the SEP-2 scores showed WMD = 17.67 (95% CI 12. 38 - 22. 97, P < 0.001) in 2 of the studies, and that of the SEP-3 scores WMD = 23.64 (95% CI 17. 49 - 29.79, P < 0.001) in 5 of the studies.
Arabidopsis thaliana SEPALLATA3 protein prokaryotic expression and purification.
Zhang et al., Dezhou, China. In Cell Mol Biol (noisy-le-grand), 2014
SEPALLATA3 (SEP3) can be attributed to E class gene of the ABCE model of floral organ development.
Protein expression and characterization of SEP3 from Arabidopsis thaliana.
Xu et al., China. In Genet Mol Res, 2014
In vitro assays indicated that SEP3 forms a tetramer after binding to DNA, but it is unclear whether DNA binding induces the tetramer, because SEP3 is often reported to form a dimer.
Digital Gene Expression Analysis Based on De Novo Transcriptome Assembly Reveals New Genes Associated with Floral Organ Differentiation of the Orchid Plant Cymbidium ensifolium.
Zhu et al., Guangzhou, China. In Plos One, 2014
Among them, eight MADS-box genes were further investigated by full-length cDNA sequence analysis and expression validation, which revealed two APETALA1/AGL9-like MADS-box genes preferentially expressed in the sepal and petal, two AGAMOUS-like genes particularly restricted to the gynostemium, and four DEF-like genes distinctively expressed in different floral organs.
Avanafil for the treatment of erectile dysfunction. An updated review.
Martínez-Salamanca et al., Madrid, Spain. In Arch Esp Urol, 2014
In all these studies, avanafil demonstrated a statistically significant improvement in erectile function (IIEF), and all the coprimary outcomes (SEP2 and SEP3) compared to placebo.
Degradation of class E MADS-domain transcription factors in Arabidopsis by a phytoplasmal effector, phyllogen.
Namba et al., Tokyo, Japan. In Plant Signal Behav, 2014
While it was shown that phyllogens target some MADS TFs, including SEP3 for degradation, it is unknown whether the other SEPs (SEP1, SEP2, and SEP4) of Arabidopsis are also degraded by them.
The effectiveness and safety of avanafil for erectile dysfunction: a systematic review and meta-analysis.
Hu et al., Xi'an, China. In Curr Med Res Opin, 2014
The pairwise meta-analysis suggested that avanafil was more effective than placebo in improving IIEF-EF (mean difference [MD]: 4.47; 95% confidence interval [CI]: 3.51 to 5.43), SEP-2 (MD: 17.41; 95% CI: 14.03 to 20.79), and SEP-3 (MD: 20.01; 95% CI: 22.98 to 37.22), with an evident dose-response relationship.
Phosphodiesterase type 5 inhibitors for the treatment of post-nerve sparing radical prostatectomy erectile dysfunction in men.
Han et al., Chengdu, China. In Sci Rep, 2013
Patients in PDE5-Is group showed significant improvement in the International Index of Erectile Function-Erectile Function domain score (IIEF-EF), Global Assessment Questionnaire (GAQ), Sexual Encounter Profile question 2 (SEP-2) and SEP-3.
SWI2/SNF2 chromatin remodeling ATPases overcome polycomb repression and control floral organ identity with the LEAFY and SEPALLATA3 transcription factors.
Wagner et al., Philadelphia, United States. In Proc Natl Acad Sci U S A, 2012
The SWI2/SNF2 ATPases physically interact with two direct transcriptional activators of class B and class C gene expression, LEAFY (LFY) and SEPALLATA3 (SEP3).
Antagonistic roles of SEPALLATA3, FT and FLC genes as targets of the polycomb group gene CURLY LEAF.
Goodrich et al., Edinburgh, United Kingdom. In Plos One, 2011
Antagonistic roles of SEPALLATA3, FT and FLC genes as targets of the polycomb group gene CURLY LEAF
A draft of the human septin interactome.
Kobarg et al., Campinas, Brazil. In Plos One, 2009
Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 group, SEPT3 group and SEPT7 group.
Target genes of the MADS transcription factor SEPALLATA3: integration of developmental and hormonal pathways in the Arabidopsis flower.
Angenent et al., Wageningen, Netherlands. In Plos Biol, 2009
SEPALLATA3 integrates and modulates different growth-related and hormonal pathways in a combinatorial fashion with other MADS-box proteins and possibly with non-MADS transcription factors.
SEPALLATA3: the 'glue' for MADS box transcription factor complex formation.
Angenent et al., Wageningen, Netherlands. In Genome Biol, 2008
higher-order complex formation is a general and essential molecular mechanism for plant MADS box protein functioning and SEP3 'glue' protein plays a pivotal role in mediating multimerization
Complexes of MADS-box proteins are sufficient to convert leaves into floral organs.
Goto et al., Uji, Japan. In Nature, 2001
Here we show that the class B proteins of Arabidopsis, PISTILLATA (PI) and APETALA3 (AP3), interact with APETALA1 (AP1, a class A protein) and SEPALLATA3 (SEP3, previously AGL9), and with AGAMOUS (AG, a class C protein) through SEP3.
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