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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Serine dehydratase-like

Top mentioned proteins: CAN, HAD, AGE, ACID, V1a
Papers on SDSL
Exercise adherence in a randomized trial of exercise on aromatase inhibitor arthralgias in breast cancer survivors: the Hormones and Physical Exercise (HOPE) study.
Irwin et al., Bethesda, United States. In J Cancer Surviv, Feb 2016
We examined means and standard deviations (SDs) for exercise adherence by demographic and medical characteristics and used the t test for mean differences.
Genome-wide association study identifies common and low-frequency variants at the AMH gene locus that strongly predict serum AMH levels in males.
Lawlor et al., Bristol, United Kingdom. In Hum Mol Genet, Feb 2016
Genetic variants at the AMH protein-coding gene showed considerable allelic heterogeneity, with both common variants [rs4807216 (PMale = 2 × 10(-49), Beta: ∼0.9 SDs per allele), rs8112524 (PMale = 3 × 10(-8), Beta: ∼0.25)] and low-frequency variants [rs2385821 (PMale = 6 × 10(-31), Beta: ∼1.2, frequency 3.6%)] independently associated with apparently large effect sizes in males, but not females.
Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury?
Shuttleworth et al., Fontenay-aux-Roses, France. In Glia, Jan 2016
Spreading depolarizations (SDs) are coordinated waves of synchronous depolarization, involving large numbers of neurons and astrocytes as they spread slowly through brain tissue.
Cholesterol-Dependent Conformational Exchange of the C-Terminal Domain of the Influenza A M2 Protein.
Howard et al., United States. In Biochemistry, Jan 2016
We used a multipronged site-directed spin-label electron paramagnetic resonance (SDSL-EPR) approach and collected data on line shapes, relaxation rates, accessibility of sites to the membrane, and distances between symmetry-related sites within the tetrameric protein.
Phase II trial of dacomitinib in patients with HER2-positive gastric cancer.
Bang et al., Seoul, South Korea. In Gastric Cancer, Dec 2015
There were 2 partial response (PRs) and 9 stable disease (SDs), resulting in 7.4 % (95 % CI, 0-17.5 %) of response rate (RR) and 40.7 % (95 % CI, 21.9-59.6
Elucidating the design principles of photosynthetic electron-transfer proteins by site-directed spin labeling EPR spectroscopy.
Lakshmi et al., Troy, United States. In Biochim Biophys Acta, Oct 2015
UNASSIGNED: Site-directed spin labeling electron paramagnetic resonance (SDSL EPR) spectroscopy is a powerful tool to determine solvent accessibility, side-chain dynamics, and inter-spin distances at specific sites in biological macromolecules.
Osteoporosis: the evolution of a diagnosis.
Cummings et al., Mölndal, Sweden. In J Intern Med, Jun 2015
The femoral neck BMD -2.5 SDs cut-off for the diagnosis of osteoporosis is arbitrarily chosen, and there is no evidence to support the notion that fracture location (except vertebral fractures) or severity is useful to discriminate osteoporotic from normal bones.
Genetic Incorporation of the Unnatural Amino Acid p-Acetyl Phenylalanine into Proteins for Site-Directed Spin Labeling.
Millhauser et al., Santa Cruz, United States. In Methods Enzymol, 2014
Site-directed spin labeling (SDSL) is a powerful tool for the characterization of protein structure and dynamics; however, its application in many systems is hampered by the reliance on unique and benign cysteine substitutions for the site-specific attachment of the spin label.
Genetically Encoded Spin Labels for In Vitro and In-Cell EPR Studies of Native Proteins.
Drescher et al., Konstanz, Germany. In Methods Enzymol, 2014
Electron paramagnetic resonance (EPR) spectroscopy in combination with site-directed spin labeling (SDSL) is a powerful approach to study the structure, dynamics, and interactions of proteins.
Exploring intrinsically disordered proteins using site-directed spin labeling electron paramagnetic resonance spectroscopy.
Belle et al., Marseille, France. In Front Mol Biosci, 2014
Among the biophysical techniques well-suited to study such highly flexible proteins, Site-Directed Spin Labeling combined with EPR spectroscopy (SDSL-EPR) is one of the most powerful, being able to reveal, at the residue level, structural transitions such as folding events.
Identifying and quantitating conformational exchange in membrane proteins using site-directed spin labeling.
Cafiso, Charlottesville, United States. In Acc Chem Res, 2014
Site-directed spin labeling (SDSL) is an EPR based approach that is particularly well-suited to high molecular-weight systems such as membrane proteins.
Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial.
Shepherd et al., Boston, United States. In Lancet Oncol, 2014
MA.27B recruited two groups of women from MA.27: those with BMD T-scores of -2·0 or more (up to 2 SDs below sex-matched, young adult mean) and those with at least one T-score (hip or spine) less than -2·0.
Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors.
Gilbertson et al., Memphis, United States. In J Clin Oncol, 2011
Four patients (three SDs + one CR) remained on treatment for more than 4 months.
A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies.
Takusagawa et al., Lawrence, United States. In Biochim Biophys Acta, 2008
The crystal structure of SDSL has been determined. Site-directed mutagenesis studies suggest that having a glycine at residue 72 of SDSL is the major reason for the reduction of its catalytic activity, in comparison with the liver enzyme (SDS).
Mutational and selective effects on copy-number variants in the human genome.
Eichler et al., Seattle, United States. In Nat Genet, 2007
Comprehensive descriptions of large insertion/deletion or segmental duplication polymorphisms (SDs) in the human genome have recently been generated.
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