Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily.
Saint Louis, United States. In Viruses, Sep 2015
For example, cowpox strain Brighton Red appears to encode 10 different PIEs: vCCI, A41, C8, M2, T4 (CPVX203), and the SECRET proteins CrmB, CrmD, SCP-1, SCP-2, and SCP-3.
Loss of L-FABP, SCP-2/SCP-x, or both induces hepatic lipid accumulation in female mice.
College Station, United States. In Arch Biochem Biophys, Sep 2015
Although roles for both sterol carrier protein-2/sterol carrier protein-x (SCP-2/SCP-x) and liver fatty acid binding protein (L-FABP) have been proposed in hepatic lipid accumulation, individually ablating these genes has been complicated by concomitant alterations in the other gene product(s).
Microarray analysis of anti-cancer effects of docosahexaenoic acid on human colon cancer model in nude mice.
Suzhou, China. In Int J Clin Exp Med, 2014
And several genes related to tumor growth and metastasis including COX2, HIF-1α, VEGF-A, COMP, MMP-1, MMP-9, SCP2, SDC3, which were down-regulated by DHA, were further confirmed in HCT-15 cell line using RT-PCR method.
Metabolic neuropathies and myopathies.
Roma, Italy. In Handb Clin Neurol, 2012
On the other hand, lysosomal (mucopolysaccharidosis, Gaucher and Fabry diseases), mitochondriopathic (mitochondrial or nuclear mutations or mDNA depletion), peroxisomal (adrenomyeloneuropathy, Refsum disease, sterol carrier protein-2 deficiency, cerebrotendinous xanthomatosis, α-methylacyl racemase deficiency) diseases are multisystemic disorders involving also the heart, liver, brain, retina, and kidney.