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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Ribosomal protein, large, P0

RPLP0, ribosomal protein P0, acidic ribosomal phosphoprotein P0, L10e, RPP0, 36B4
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: GAPDH, POLYMERASE, CAN, ACID, Actin
Papers on RPLP0
Identification of Suitable Reference Genes for Peripheral Blood Mononuclear Cell Subset Studies in Multiple Sclerosis.
Romme Christensen et al., Copenhagen, Denmark. In Scand J Immunol, Jan 2016
Eight candidate reference genes (CASC3, EEF1A1, GAPDH, HPRT1, RPLP0, UBC, UBE2D2 and YWHAZ) were analysed using normfinder and genorm algorithms to identify the most stably expressed genes.
Formation of Potato Virus A-Induced RNA Granules and Viral Translation Are Interrelated Processes Required for Optimal Virus Accumulation.
Mäkinen et al., Helsinki, Finland. In Plos Pathog, Dec 2015
We used confocal microscopy to demonstrate the presence of host RNA binding proteins including acidic ribosomal protein P0, argonaute 1 (AGO1), oligouridylate-binding protein 1 (UBP1), varicose (VCS) and eukaryotic initiation factor iso4E (eIF(iso)4E) in these potyvirus-induced RNA granules.
Evaluation of reference genes for gene expression studies in human brown adipose tissue.
Svensson et al., Göteborg, Sweden. In Adipocyte, Oct 2015
Seven genes (FAM96B, GNB1, GNB2, HUWE1, PSMB2, RING1 and TPT1) identified by microarray analysis, and 8 commonly used reference genes (18S, B2M, GAPDH, LRP10, PPIA, RPLP0, UBC, and YWHAZ) were selected and further analyzed by quantitative PCR in both BAT containing perirenal adipose tissue and subcutaneous adipose tissue.
Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts.
Nawrot et al., Belgium. In Environ Health Perspect, Sep 2015
Relative placental mtDNA content was determined as the ratio of two mitochondrial genes (MT-ND1 and MTF3212/R3319) to two control genes (RPLP0 and ACTB).
Identification of Suitable Reference Genes for Normalization of Real-Time Quantitative Polymerase Chain Reaction in an Intestinal Graft-Versus-Host Disease Mouse Model.
Xu et al., Xuzhou, China. In Transplant Proc, Jul 2015
Transcription levels of 9 candidate genes, B2M, SDHA, HPRT, ACTB, GAPDH, HMBS, TBP, YWHAZ, and RPLP0, in each tissue were measured with the use of RT-qPCR.
High efficacy of a 20 amino acid peptide of the acidic ribosomal protein P0 against the cattle tick, Rhipicephalus microplus.
Estrada et al., Havana, Cuba. In Ticks Tick Borne Dis, Jun 2015
We have identified an immunogenic region of ribosomal protein P0 from Rhipicephalus spp.
The dilution effect and the importance of selecting the right internal control genes for RT-qPCR: a paradigmatic approach in fetal sheep.
Braun et al., Berlin, Germany. In Bmc Res Notes, 2014
The usefulness of RNA18S, ACTB, HPRT1, RPLP0, PPIA and TUBB as ICGs was analyzed according to effects of early dexamethasone (DEX) treatment, gender, and gestational age by two approaches: (1) the classical approach where raw (i.e., not normalized) RT-qPCR data of tested ICGs were statistically analyzed and the best ICG selected based on absence of any significant effect; (2) used of published algorithms.
Selection of reference genes for gene expression studies related to intramuscular fat deposition in Capra hircus skeletal muscle.
Wang et al., Chengdu, China. In Plos One, 2014
In the present study, eight reference genes (PPIB, HMBS, RPLP0, B2M, YWHAZ, 18S, GAPDH and ACTB) were evaluated by three different algorithms (geNorm, NormFinder and BestKeeper) in two types of muscle tissues (longissimus dorsi muscle and biceps femoris muscle) across different developmental stages.
Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood.
Holdt et al., München, Germany. In Plos One, 2014
TL was assessed by qPCR, and normalized to the single copy reference gene 36B4 using two established single-plex and a new multiplex protocol.
Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain.
Abisambra et al., Lexington, United States. In J Alzheimers Dis, 2014
We found that tau associated equally with the ribosomal protein L28 but more robustly with the ribosomal protein P0.
Telomere length is highly inherited and associated with hyperactivity-impulsivity in children with attention deficit/hyperactivity disorder.
de Miranda et al., Belo Horizonte, Brazil. In Front Mol Neurosci, 2014
TL was measured with a quantitative polymerase chain reaction method with telomere signal normalized to the signal from a single copy gene (36B4) to generate a T/S ratio.
Disruption of the ribosomal P complex leads to stress-induced autophagy.
Lleonart et al., Barcelona, Spain. In Autophagy, 2014
The human ribosomal P complex, which consists of the acidic ribosomal P proteins RPLP0, RPLP1, and RPLP2 (RPLP proteins), recruits translational factors, facilitating protein synthesis.
Autoantibody profiling on human proteome microarray for biomarker discovery in cerebrospinal fluid and sera of neuropsychiatric lupus.
Li et al., Beijing, China. In Plos One, 2014
The positive rates of 4 autoantibodies in CSF specimens were significantly different between the SLE (i.e., NPSLE and non-NPSLE) and control groups: anti-ribosomal protein RPLP0, anti-RPLP1, anti-RPLP2, and anti-TROVE2 (also known as anti-Ro/SS-A).
Selection and Evaluation of Tissue Specific Reference Genes in Lucilia sericata during an Immune Challenge.
Franta et al., Gießen, Germany. In Plos One, 2014
We therefore selected 10 candidate reference genes encoding products from different functional classes (18S rRNA, 28S rRNA, actin, β-tubulin, RPS3, RPLP0, EF1α, PKA, GAPDH and GST1).
Solution structure of the natively assembled yeast ribosomal stalk determined by small-angle X-ray scattering.
Tchórzewski et al., Lublin, Poland. In Biochem J, 2012
The model of the pentameric ribosomal stalk complex displays three distinct lobes, which may correspond to the individual P1-P2 heterodimers anchored to the C-terminal domain of the P0 protein 60S subunit.
P1 and P2 protein heterodimer binding to the P0 protein of Saccharomyces cerevisiae is relatively non-specific and a source of ribosomal heterogeneity.
Ballesta et al., Madrid, Spain. In Nucleic Acids Res, 2012
The reported results support that while most ribosomes contain a P1alpha/P2beta-P0-P1beta/P2alpha structure in normal conditions, the stalk assembly mechanism can generate alternative compositions, which have been previously detected in the cell.
Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors.
Lleonart et al., Barcelona, Spain. In Hum Pathol, 2011
P proteins are up-regulated in a considerable number of patients with the most common types of cancer.
In vivo formation of a stable pentameric (P2alpha/P1beta)-P0-(P1alpha/P2beta) ribosomal stalk complex in Saccharomyces cerevisiae.
Remacha et al., Madrid, Spain. In Yeast, 2010
The authors have found that neither P1 nor P2 directly interact with P0 unless the endogenous heterodimer partner is being expressed in the cell.
Identification of genes for normalization of quantitative real-time PCR data in ovarian tissues.
Song et al., Beijing, China. In Acta Biochim Biophys Sin (shanghai), 2010
Results show that RPL4, RPLP0, and HSPCB were the most stable reference genes in ovarian tissues.
Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation.
Wahl et al., Göttingen, Germany. In Cell, 2005
We present crystal structures of Thermotoga maritima L10 in complex with three L7/12 N-terminal-domain dimers, refine the structure of an archaeal L10E N-terminal domain on the 50S subunit, and identify these elements in cryo-electron-microscopic reconstructions of Escherichia coli ribosomes.
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