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Ribosomal protein L29

RPL29, ribosomal protein L29, YL43, heparin/heparan sulfate-interacting protein, HP/HS interacting protein
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, CAN, POLYMERASE, fibrillin-1, GAPDH
Papers on RPL29
Synthetic chimeras with orthogonal ribosomal proteins increase translation yields by recruiting mRNA for translation as measured by profiling active ribosomes.
Contreras et al., Austin, United States. In Biotechnol Prog, Feb 2016
In this work, we exploit an engineered version of the E. coli ribosomal protein L29 (L4H2) as a fusion partner for enhancing cellular expression of proteins that are poorly expressed in bacteria.
Validation of reference genes for quantitative real-time PCR in Périgord black truffle (Tuber melanosporum) developmental stages.
Pacioni et al., L'Aquila, Italy. In Phytochemistry, Aug 2015
In this study, we present a morphological and microscopical classification of the developmental stages of T. melanosporum fruit body, and investigate the expression levels of 12 candidate reference genes (18S rRNA; 5.8S rRNA; Elongation factor 1-alpha; Elongation factor 1-beta; α-tubulin; 60S ribosomal protein L29; β-tubulin; 40S ribosomal protein S1; 40S ribosomal protein S3; Glucose-6-phosphate dehydrogenase; β-actin; Ubiquitin-conjugating enzyme).
Serum anti-60S ribosomal protein L29 antibody as a novel prognostic marker for unresectable pancreatic cancer.
Yamamoto et al., In Digestion, 2014
BACKGROUND/AIMS: Recently, we found the presence of anti-60S ribosomal protein L29 antibody (anti-RPL29) in human sera, inhibiting the proliferation of pancreatic cancer cells in vitro.
Gene expression analysis in MCF-7 breast cancer cells treated with recombinant bromelain.
Hashim et al., Kuala Lumpur, Malaysia. In Appl Biochem Biotechnol, 2014
These genes are RNA-binding motif, single-stranded interacting protein 1 (RBMS1), ribosomal protein L29 (RPL29), glutathione S-transferase mu 2 (GSTM2), C15orf32, Akt3, B cell translocation gene 1 (BTG1), C6orf62, C7orf60, kinesin-associated protein 3 (KIFAP3), FBXO11, AT-rich interactive domain 4A (ARID4A), COPS2, TBPL1|SLC2A12, TMEM59, SNORD46, glioma tumor suppressor candidate region gene 2 (GLTSCR2), and LRRFIP.
Reference genes for quantitative RT-PCR data in gastric tissues and cell lines.
Smith et al., São Paulo, Brazil. In World J Gastroenterol, 2013
METHODS: The suitability of genes ACTB, B2M, GAPDH, RPL29, and 18S rRNA was assessed in 21 matched pairs of neoplastic and adjacent non-neoplastic gastric tissues from patients with gastric adenocarcinoma, 27 normal gastric tissues from patients without cancer, and 4 cell lines using reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR).
Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
Glaser et al., Stockholm, Sweden. In Proc Natl Acad Sci U S A, 2013
Short mitochondrial targeting peptides (presequence of the ribosomal protein L29 and presequence of 1-aminocyclopropane-1-carboxylic acid deaminase 1) and N- and C-terminal fragments derived from the presequence of the ATPase beta subunit ranging in size from 11 to 20 aa could be degraded.
[Effect of Helicobacter pylori eradication on the expression level of SATB1 and c-Myc genes in gastric mucosa of patients with family history of gastric cancer].
Nawrot et al., In Pol Merkur Lekarski, 2013
The level of each mRNA was normalized to the levels of mRNA of two reference genes, RPL29 and GAPDH.
Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines.
Roschke et al., Bethesda, United States. In Cancer Genet, 2013
For the first time, LINGO2, RBFOX1/A2BP1, RPL29, DUSP7, and CCSER1/FAM190A were found to be homozygously deleted in MMt, and some of these genes could be new tumor suppressor genes for MMt.
Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS.
Liu et al., New York City, United States. In Pediatr Blood Cancer, 2013
To analyze the effect of SBDS on 60S subunit maturation in A549 cells, subunit localization was assessed by transfection with a vector expressing a fusion between human RPL29 and GFP: we found a higher percentage of SBDS-depleted cells with nuclear localization of 60S subunits.
Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice.
Hodivala-Dilke et al., London, United Kingdom. In Dis Model Mech, 2013
Cellular ribosomal protein L29 (RPL29) is known to be important in protein synthesis, but its function during angiogenesis has never been described before.
Reference gene selection for qRT-PCR analysis in the sweetpotato whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae).
Zhang et al., Changsha, China. In Plos One, 2012
Specifically, for biotic conditions including host plant, acquisition of a plant virus, developmental stage, tissue (body region of the adult), and whitefly biotype, ribosomal protein L29 was the most stable reference gene.
Reverse transcription quantitative real-time polymerase chain reaction reference genes in the spared nerve injury model of neuropathic pain: validation and literature search.
Suter et al., Lausanne, Switzerland. In Bmc Res Notes, 2012
These were: Actin beta (Actb), Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), ribosomal proteins 18S (18S), L13a (RPL13a) and L29 (RPL29), hypoxanthine phosphoribosyltransferase 1 (HPRT1) and hydroxymethylbilane synthase (HMBS).
Silencing expression of ribosomal protein L26 and L29 by RNA interfering inhibits proliferation of human pancreatic cancer PANC-1 cells.
Chen et al., Shanghai, China. In Mol Cell Biochem, 2012
As a result, ribosomal proteins L26 and L29 (RPL26 and RPL29) were dramatically upregulated by KRAS-shRNA specifically.
Proteomic analysis in giant axonal neuropathy: new insights into disease mechanisms.
Van Coster et al., Gent, Belgium. In Muscle Nerve, 2012
RESULTS: Among the dysregulated proteins were ribosomal protein L29, ribosomal protein L37, galectin-1, glia-derived nexin, and aminopeptidase N. Also, nuclear proteins linked to formin-binding proteins were found to be dysregulated.
Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation.
Dai et al., Portland, United States. In J Biol Chem, 2010
Knockdown of L29 or L30 enhanced the interaction of MDM2 with L11 and L5 and markedly inhibited MDM2-mediated p53 ubiquitination, suggesting that direct perturbation of 60 S ribosomal biogenesis activates p53 via L11- and L5-mediated MDM2 suppression.
Effect of HIP/ribosomal protein L29 deficiency on mineral properties of murine bones and teeth.
Kirn-Safran et al., Newark, United States. In Bone, 2010
Consistent with the HIP/RPL29-null bone phenotype, HIP/RPL29-deficient teeth also showed reduced geometric properties accompanied with relative increased mineral densities of both dentin and enamel.
Ribosomal protein L29/HIP deficiency delays osteogenesis and increases fragility of adult bone in mice.
Kirn-Safran et al., Newark, United States. In J Orthop Res, 2009
L29/HIP may have a role in preventing osteogenesis and fragility of adult bone in mice
HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses.
Carson et al., Newark, United States. In J Cell Biochem, 2009
HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses
Hip is a pro-survival substrate of granzyme B.
Craik et al., United States. In J Biol Chem, 2007
Hip is a pro-survival substrate of granzyme B
Altered ribosomal protein L29 in a cycloheximide-resistant strain of Saccharomyces cerevisiae.
Piepersberg et al., Regensburg, Germany. In Curr Genet, 1980
A spontaneous high-level cycloheximide-resistant mutant of the yeast Saccharomyces cerevisiae (strain cy32) is found to have an altered protein of the large subunit (60S) of cytoplasmic ribosomes, namely protein L29.
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