Scutellarin Reduces Endothelium Dysfunction through the PKG-I Pathway.
Kunming, China. In Evid Based Complement Alternat Med, 2014
In rat CIR model, wire myography demonstrated that SCU (45 and 90 mg/kg, i.v.) significantly reduced ischemic size by partially restoring the endothelium dependent vasodilation of BA; PKG inhibitor Rp-8-Br-cGMPS (50 μg/kg, i.v.) reversed this protection of SCU in CIR rats.
[Genomics of type I diabetes mellitus and its late complications].
Moscow, Russia. In Mol Biol (mosk), 2004
With these families, linkage to T1DM was demonstrated for CTLA4 (IDDM12, 2q32.1-q33), which codes for a T-cell surface antigen, and PDCD2 (IDDM8, 6q25-q27), which is homologous to the mouse programmed cell death activator gene.