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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Ring finger protein

RNF6, RING-H2 protein
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Ubiquitin, p53, ACID, Pirh2, CAN
Papers on RNF6
PtaRHE1, a Populus tremula × Populus alba RING-H2 protein of the ATL family, has a regulatory role in secondary phloem fibre development.
Baucher et al., Brussels, Belgium. In Plant J, Jun 2015
Previously, we have shown that the expression of PtaRHE1, encoding a Populus tremula × Populus alba RING-H2 protein with E3 ubiquitin ligase activity, is associated with tissues undergoing secondary growth.
Human Pirh2 is a novel inhibitor of prototype foamy virus replication.
Liu et al., Wuhan, China. In Viruses, Apr 2015
Herein, we identified human p53-induced RING-H2 protein (Pirh2) as a novel inhibitor of prototype foamy virus.
Does PtaRHE1, a poplar RING-H2 protein, play a role in water conduction through ABA signaling?
Baucher et al., Brussels, Belgium. In Plant Signal Behav, 2013
RING (REALLY INTERESTING NEW GENE) proteins with E3 ligase activity are largely represented in plants.
Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.
Qiu et al., Baltimore, United States. In J Biol Chem, 2012
We also showed that PIM-1S induced Ser-213 phosphorylation destabilizes AR by recruiting the ubiquitin E3 ligase Mdm2 and promotes AR degradation in a cell cycle-dependent manner, while PIM-1L-induced Thr-850 phosphorylation stabilizes AR by recruiting the ubiquitin E3 ligase RNF6 and promotes AR-mediated transcription under low-androgen conditions.
Proteomic analysis of ubiquitination-associated proteins in a cisplatin-resistant human lung adenocarcinoma cell line.
Qiu et al., Chongqing, China. In Int J Mol Med, 2012
The results of western blotting and confocal laser scanning microscopy indicated that the expression levels of the E3 ubiquitin ligases RNF6, LRSAM1 and TRIM25 in A549 cells were significantly lower than those in the A549/CDDP cell line.
Identification of Pirh2E and Pirh2F, two additional novel isoforms of Pirh2 ubiquitin ligase from human hepatocellular liver carcinoma cell line.
He et al., Wuhan, China. In Biomed Mater Eng, 2011
Recent researches have shown that E3 ubiquitin ligases Pirh2 (p53-induced RING-H2 protein) is highly expressed in HCC cell lines and is correlated with poor survival and prognostic in patients with HCC; however, the function of Pirh2 in the genesis and the development of HCC remains unclear.
Ectopic expression of PtaRHE1, encoding a poplar RING-H2 protein with E3 ligase activity, alters plant development and induces defence-related responses.
Baucher et al., Brussels, Belgium. In J Exp Bot, 2009
In the present report, experiments were performed to unravel the role of the poplar gene PtaRHE1, coding for a RING-H2 protein.
Cell cycle deregulation by a poxvirus partial mimic of anaphase-promoting complex subunit 11.
Mercer et al., Dunedin, New Zealand. In Proc Natl Acad Sci U S A, 2009
APC consists of at least 12 subunits with the catalytic core formed by a scaffold protein, APC2, and a RING-H2 protein, APC11.
p53-induced RING-H2 protein, a novel marker for poor survival in hepatocellular carcinoma after hepatic resection.
Wu et al., Changsha, China. In Cancer, 2009
BACKGROUND: Currently, the role of p53-induced RING-H2 protein (PIRH2) in the development of hepatocellular carcinoma (HCC) remains unknown.
The Arabidopsis RING finger E3 ligase RHA2a is a novel positive regulator of abscisic acid signaling during seed germination and early seedling development.
Li et al., Beijing, China. In Plant Physiol, 2009
Here, we characterize the biological function of the Arabidopsis (Arabidopsis thaliana) RING-H2 protein RHA2a in ABA signaling.
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.
Qiu et al., Baltimore, United States. In Cancer Cell, 2009
We have identified a ubiquitin E3 ligase, RNF6, as an AR-associated protein in a proteomic screen.
Intraplastidial trafficking of a phage-type RNA polymerase is mediated by a thylakoid RING-H2 protein.
Lerbs-Mache et al., Grenoble, France. In Proc Natl Acad Sci U S A, 2008
The plastid genome of dicotyledonous plants is transcribed by three different RNA polymerases; an eubacterial-type enzyme, PEP; and two phage-type enzymes, RPOTp and RPOTmp.
Cloning and identification of a novel RNF6 transcriptional splice variant Spg2 in human development.
Ma et al., Nanjing, China. In Sci China C Life Sci, 2008
Results describe thet cloning and identification of a novel RNF6 transcriptional splice variant, Spg2, in human development.
PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53.
Yang et al., Cleveland, United States. In Biochem Biophys Res Commun, 2008
Pirh2 (P53 induced RING-H2 protein) is a p53 inducible E3 ligase involved in the ubiquitination of p53, while the mechanisms to regulate its activities are largely unknown.
Lim kinases, regulators of actin dynamics.
Bernard, Australia. In Int J Biochem Cell Biol, 2006
Rnf6 is an E3 ubiquitin ligase responsible for LIMK degradation in neurons.
The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.
Bach et al., Hamburg, Germany. In Genes Dev, 2005
Rnf6 controls cellular LIMK1 concentrations and indicate a new function for the ubiquitin/proteasome system in regulating local growth cone actin dynamics
Gene control in germinal differentiation: RNF6, a transcription regulatory protein in the mouse sertoli cell.
Rassoulzadegan et al., Nice, France. In Mol Cell Biol, 2002
Functional anaylysis of the mouse homolog
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