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Tripartite motif containing 49

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11. [provided by RefSeq, Aug 2010] (from NCBI)
Top mentioned proteins: PCNA, HAD, SS-A, metabotropic glutamate receptor, AURKA
Papers on RNF18
Differential regulation of abundance and deadenylation of maternal transcripts during bovine oocyte maturation in vitro and in vivo.
Dalbi├Ęs-Tran et al., Tours, France. In Bmc Dev Biol, 2006
Four genes are characterized here for the first time in bovine: ring finger protein 18 (RNF18) and breast cancer anti-estrogen resistance 4 (BCAR4), whose oocyte preferential expression was not previously reported in any species, as well as Maternal embryonic leucine zipper kinase (MELK) and STELLA.
Characterization of mGluR5R, a novel, metabotropic glutamate receptor 5-related gene.
Paulsen et al., Cambridge, United States. In Brain Res Mol Brain Res, 2003
The N-terminus of mGluR5R is highly similar to the extracellular domain of metabotropic glutamate receptor 5 (mGluR5) whereas the C-terminus bears similarity to the testis-specific gene, RNF18.
Isolation of a cDNA for a novel human RING finger protein gene, RNF18, by the virtual transcribed sequence (VTS) approach(1).
Saito et al., Kisarazu, Japan. In Biochim Biophys Acta, 2000
We designated the novel gene as RNF18.
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