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Ribosomal protein L19

ribosomal protein L19, RPL19
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, GAPDH, POLYMERASE, ACID, SET
Papers on ribosomal protein L19
Evaluation of reference gene suitability for quantitative expression analysis by quantitative polymerase chain reaction in the mandibular condyle of sheep.
Hu et al., Xi'an, China. In Mol Med Report, Oct 2015
The results obtained from the four methods demonstrated a similar trend: RPL19, ACTB, and PGK1 were the most stably expressed reference genes in the sheep mandibular condyle.
Validation of endogenous control reference genes for normalizing gene expression studies in endometrial carcinoma.
Konje et al., Doha, Qatar. In Mol Hum Reprod, Sep 2015
The mathematical software packages geNorm qBasePLUS identified Pumilio homolog 1 (Drosophila) (PUM1), ubiquitin C (UBC), phosphoglycerate kinase (PGK1), mitochondrial ribosomal protein L19 (MRPL19) and peptidylpropyl isomerase A (cyclophilin A) (PPIA) as the best reference gene combination, whilst NormFinder identified MRPL19 as the best single reference gene, with importin 8 (IPO8) and PPIA being the best combination of two reference genes.
Identification of stably expressed reference genes for RT-qPCR data normalization in defined localizations of cyclic bovine ovaries.
Kaessmeyer et al., Berlin, Germany. In Anat Histol Embryol, Jun 2015
Expression profiles of twelve potential reference genes (GAPDH, ACTB, YWHAZ, HPRT1, SDHA, UBA52, POLR2C, RPS9, ACTG2, H3F3B, RPS18 and RPL19) were analysed.
The effects of RNA interference targeting Bactrocera dorsalis ds-Bdrpl19 on the gene expression of rpl19 in non-target insects.
Zhang et al., Wuhan, China. In Ecotoxicology, Apr 2015
In this paper, we investigated the effects of dsRNA targeting rpl19 from Bactrocera dorsalis on non-target insects in citrus ecological systems by feeding the dsRNA to Bactrocera minax, Apis mellifera and Diachasmimorpha longicaudata.
Differential Genes Expression between Fertile and Infertile Spermatozoa Revealed by Transcriptome Analysis.
Rajender et al., Lucknow, India. In Plos One, 2014
Some transcripts were specific to the normozoospermic group (up-regulated: CAPNS1, FAM153C, ARF1, CFL1, RPL19, USP22; down-regulated: ZNF90, SMNDC1, c14orf126, HNRNPK), while some were specific to the asthenozoospermic group (up-regulated: RPL24, HNRNPM, RPL4, PRPF8, HTN3, RPL11, RPL28, RPS16, SLC25A3, C2orf24, RHOA, GDI2, NONO, PARK7; down-regulated: HNRNPC, SMARCAD1, RPS24, RPS24, RPS27A, KIFAP3).
A de novo transcriptome and valid reference genes for quantitative real-time PCR in Colaphellus bowringi.
Wang et al., Wuhan, China. In Plos One, 2014
Among these candidate genes, EF1α, ACT1, and RPL19 proved to be the most stable reference genes for different reverse transcriptase quantitative polymerase chain reaction experiments in C. bowringi.
Plant Ribosomal Proteins, RPL12 and RPL19, Play a Role in Nonhost Disease Resistance against Bacterial Pathogens.
Mysore et al., Ardmore, United States. In Front Plant Sci, 2014
Genes encoding ribosomal proteins, RPL12 and RPL19, were identified in the screening.
Bypassing hazard of housekeeping genes: their evaluation in rat granule neurons treated with cerebrospinal fluid of multiple sclerosis subjects.
Burgal-Marti et al., Valencia, Spain. In Front Cell Neurosci, 2014
GeNorm identified transferrin receptor (Tfrc) and microglobulin beta-2 (B2m) the most stable genes followed by ribosomal protein L19 (Rpl19) whereas β-actin (ActB) and glyceraldehyde-3-phosphate-dehydrogenase (Gapdh) the most fluctuated ones in these neurons.
Characterization of the pattern of ribosomal protein L19 production during the lifecycle of Leishmania spp.
Cruz et al., Ribeirão Preto, Brazil. In Exp Parasitol, 2014
Analysis of a region of chromosome 6 from Leishmania major (Iribar et al.) showed that the transcript of a putative L19 ribosomal protein (RPL19) was most abundant at the amastigote stage.
Ribosomal protein L19 overexpression activates the unfolded protein response and sensitizes MCF7 breast cancer cells to endoplasmic reticulum stress-induced cell death.
Kim et al., Seoul, South Korea. In Biochem Biophys Res Commun, 2014
Ribosomal protein L19 is overexpressed in breast cancer cells by amplification and copy number variation.
Reference genes for quantitative gene expression studies in multiple avian species.
Gruber et al., Berlin, Germany. In Plos One, 2013
Here we report testing a set for 14 candidate reference genes (18S, ABL, GAPDH, GUSB, HMBS, HPRT, PGK1, RPL13, RPL19, RPS7, SDHA, TFRC, VIM, YWHAZ) on different tissues of the mallard (Anas platyrhynchos), domestic chicken (Gallus gallus domesticus), common crane (Grus grus), white-tailed eagle (Haliaeetus albicilla), domestic turkey (Meleagris gallopavo f. domestica), cockatiel (Nymphicus hollandicus), Humboldt penguin (Sphenicus humboldti), ostrich (Struthio camelus) and zebra finch (Taeniopygia guttata), spanning a broad range of the phylogenetic tree of birds.
Ranking and selection of MII oocytes in human ICSI cycles using gene expression levels from associated cumulus cells.
Pitman et al., Wellington, New Zealand. In Hum Reprod, 2013
MATERIALS, SETTING, METHODS: Expression levels of eight candidate genes (HAS2, FSHR, SLC2A4, ALCAM, SFRP2, VCAN, NRP1 and PR), corrected for RPL19, were measured in individual CC masses using multiplex QPCR.
A simple PCR-based strategy for estimating species-specific contributions in chimeras and xenografts.
Schneider et al., San Francisco, United States. In Development, 2013
Species-specific primers for reverse transcription quantitative real-time PCR (RT-qPCR) were designed by identifying silent mutations in quail, duck, chicken, mouse and human ribosomal protein L19 (RPL19).
Reference gene selection for quantitative PCR studies in sheep neutrophils.
Hall et al., Corvallis, United States. In Int J Mol Sci, 2012
We investigated 11 potential neutrophil reference genes (RPL19, GAPDH, ACTB, B2M, HPRT, G6PD, TFRC, PGK1, YWHAZ, SDHA and GYPC) for sheep under disease conditions of foot rot (FR) and with or without Se supplementation.
Microvascular biodistribution of L19-SIP in angiogenesis targeting strategies.
Vajkoczy et al., Berlin, Germany. In Eur J Cancer, 2011
L19-SIP shows a time and blood-flow dependent microvascular biodistribution process with angiogenic sprouts as preferential binding sites followed by secondary extravasation of the antibody
siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer.
Foster et al., Liverpool, United Kingdom. In Plos One, 2010
posttranscriptional silencing of gene RPL19 using RNAi not only abrogates the malignant phenotype of PC-3M prostate cancer cells but is selective with respect to transcription and translation of other genes
Identification of ribosomal protein L19 as a novel tumor antigen recognized by autologous cytotoxic T lymphocytes in lung adenocarcinoma.
Yasumoto et al., Kitakyūshū, Japan. In Cancer Sci, 2010
RPL19 is a novel overexpressed antigen which may therefore be a useful candidate as a target for specific immunotherapy.
The targeted immunocytokine L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer.
Menrad et al., Berlin, Germany. In Clin Cancer Res, 2008
L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer
Ribosomal protein l19 is a prognostic marker for human prostate cancer.
Foster et al., Liverpool, United Kingdom. In Clin Cancer Res, 2006
The increased RPL19 expression to be highly predictive of shorter patient survival (P < 0.05), revealing RPL19 to be a sensitive predictor of prostate cancer progression.
Protein signatures distinctive of alpha proteobacteria and its subgroups and a model for alpha-proteobacterial evolution.
Gupta, Hamilton, Canada. In Crit Rev Microbiol, 2004
A number of proteins contain conserved indels that are specific for Rickettsiales (XerD integrase and leucine aminopeptidase), Rickettsiaceae (Mfd, ribosomal protein L19, FtsZ, Sigma 70 and exonuclease VII), or Anaplasmataceae (Tgt and RP-314), and they distinguish these groups from all others.
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