Rho GTPase isoforms in cell motility: Don't fret, we have FRET.
United States. In Cell Adh Migr, 2013
Clearly, additional efforts are still required to produce biosensor systems capable of detecting other isoforms of Rho GTPases including RhoB, Rac2/3, RhoG, etc. Through such efforts, we will uncover the isoform-specific roles of these near-identical proteins in living cells, clearly an important area of the Rho GTPase biology that is not yet fully appreciated.
Immunohistochemical expression of Rho GTPases in ameloblastomas.
Florianópolis, Brazil. In J Oral Pathol Med, 2012
RhoB may have a key role in ameloblastoma neoplastic epithelial cell phenotype determination, as well as in variant and subtype determination; different results of RhoB are observed in follicular and plexiform ameloblastomas.
Actin' up: RhoB in cancer and apoptosis.
United States. In Nat Rev Cancer, 2001
RhoB is dispensable for normal cell physiology but it has a suppressor or negative modifier function in stress-associated processes including cancer.