Small GTPases in peroxisome dynamics.
Heidelberg, Germany. In Biochim Biophys Acta, Feb 2016
In its GTP-bound form RhoA activates a regulatory cascade involving Rho kinaseII and non-muscle myosinIIA.
Reaching the brain: Advances in optic nerve regeneration.
In Exp Neurol, Jan 2016
More recently, some degree of regeneration has been achieved through the optic nerve itself by factors associated with intraocular inflammation (oncomodulin) or by altering levels of particular transcription factors (Klf-4, -9, c-myc), cell-intrinsic suppressors of axon growth (PTEN, SOCS3), receptors to cell-extrinsic inhibitors of axon growth (Nogo receptor, LAR, PTP-σ) or the intracellular signaling pathway activated by these receptors (RhoA).
Pathophysiological Functions of Rnd3/RhoE.
More papers using
Zhanjiang, China. In Compr Physiol, 2014
The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity.
ERK5 promotes Src-induced podosome formation by limiting Rho activation
In The Journal of Cell Biology, 1999
... (4F11) were obtained from Millipore; anti-Fra1, anti-GFP, anti-ROCK, anti-Rac1, anti-MEF2, anti-VP16, anti-CDC42, anti-myc (9E10), and anti-RhoA were obtained from Santa Cruz Biotechnology, Inc.; anti-GAPDH was obtained ... The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis
In The Journal of Cell Biology, 1997
... phosphotyrosine (clones 10, 77, 21, 165, 102, 30, and RC20, respectively, obtained from Transduction Laboratories), RhoA (clone 26C4; Santa Cruz Biotechnology, Inc.), and vinculin (clone ...