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Rh blood group, CcEe antigens

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms. [provided by RefSeq, Jul 2008] (from NCBI)
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Top mentioned proteins: RhD, ACID, HAD, POLYMERASE, CAN
Papers using RHCE antibodies
Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes
Mungenast Alison E., In Neural Plasticity, 2007
... O, Sigma), RHC-80267 (60 mM stock in DMSO, Biomol), R59949 (25 mM stock in ...
The cannabinoid CB1 receptor mediates retrograde signals for depolarization-induced suppression of inhibition in cerebellar Purkinje cells
Lindgren Clark et al., In The European Journal of Neuroscience, 2001
... 1,6-Bis-(cyclohexyloximinocarbonylamino)-hexane (RHC-80267) was purchased from Biomol (Plymouth Meeting, PA, USA) ...
Papers on RHCE
A novel fluorescent probe for Cr(3+) based on rhodamine-crown ether conjugate and its application to drinking water examination and bioimaging.
Song et al., Changchun, China. In Spectrochim Acta A Mol Biomol Spectrosc, Apr 2016
A trivalent chromium (Cr(3+)) fluorescence probe (RhC) was designed and synthesized via Schiff base reaction based on rhodamine-crown ether conjugate.
Comprehensive analysis of RHD splicing transcripts reveals the molecular basis for the weak anti-D reactivity of Del -red blood cells.
Tseng et al., Taiwan. In Transfus Med, Feb 2016
BACKGROUND: Of the Rh blood type, Del is a rare variant that elicits the weakest anti-D reactivity.
Evidence for Decoupled Electron and Proton Transfer in the Electrochemical Oxidation of Ammonia on Pt(100).
Koper et al., In J Phys Chem Lett, Feb 2016
UNASSIGNED: The two traditional mechanisms of the electrochemical ammonia oxidation consider only concerted proton-electron transfer elementary steps and thus they predict that the rate-potential relationship is independent of the pH on the pH-corrected RHE potential scale.
Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.
Zhou et al., Guangzhou, China. In Genet Test Mol Biomarkers, Jan 2016
AIMS: This study aimed to compare the intron 4 sequence of the RHD and RHCE genes from Han Chinese, Tibetans, and Mongols, and explore its polymorphisms.
Comprehensive red blood cell and platelet antigen prediction from whole genome sequencing: proof of principle.
MedSeq Project et al., Boston, United States. In Transfusion, Jan 2016
RESULTS: Some major differences and alignment issues were found when attempting to convert the conventional cDNA to human reference genome sequences for the following genes: ABO, A4GALT, RHD, RHCE, FUT3, ACKR1 (previously DARC), ACHE, FUT2, CR1, GCNT2, and RHAG.
Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection.
Hsue et al., San Francisco, United States. In Plos One, Dec 2015
Participants with a PASP ≥ 30 mmHg (n = 65) underwent right heart catheterization (RHC) to definitively diagnose PAH.
Assessment of N-terminal prohormone B-type natriuretic peptide as a measure of vascular and ventricular function in pediatric pulmonary arterial hypertension.
Shandas et al., Aurora, United States. In Pulm Circ, Dec 2015
We retrospectively analyzed right heart catheterization (RHC) and serum biochemical analysis data ([Formula: see text]) for a pediatric PAH cohort with no sign of left ventricular dysfunction.
Controlled Growth of Ferrihydrite Branched Nanosheet Arrays and Their Transformation to Hematite Nanosheet Arrays for Photoelectrochemical Water Splitting.
Qi et al., Beijing, China. In Acs Appl Mater Interfaces, Nov 2015
After a simple postgrowth Ti-doping process, the resulting Ti-doped α-Fe2O3 nanosheet arrays showed a good PEC performance for water splitting with a photocurrent density of 1.79 mA/cm(2) at 1.6 V vs RHE under AM 1.5G illumination (100 mW/cm(2)).
Insights into RHCE Molecular Analysis in Samples with Partial D Variants: the Experience of Western France.
Férec et al., Brest, France. In Transfus Med Hemother, Nov 2015
RHCE exons 1-7 were directly sequenced, and expression of Rh antigens was predicted on the basis of the molecular data.
Underrated value of repeated right heart catheterization in pulmonary hypertension with heart failure-a case of persisted pulmonary arterial hypertension after treatment for biventricular failure.
Lee et al., Seoul, South Korea. In J Thorac Dis, Oct 2015
Right heart catheterization (RHC) showed elevated mean pulmonary arterial pressure (mPAP) and pulmonary capillary wedge pressure (PCWP).
Cyclic AMP (cAMP) signaling in melanocytes and melanoma.
Setaluri et al., Madison, United States. In Arch Biochem Biophys, 2015
Some MC1R polymorphisms produce cAMP signaling impairment and pigmentary phenotypes such as the red head color and fair skin phenotype (RHC) that is usually associated with higher risk for melanoma development.
A novel therapeutic approach in pulmonary arterial hypertension as a complication of adult-onset Still's disease: targeting IL-6.
Efthimiou et al., New York City, United States. In Int J Rheum Dis, 2014
Improvement of systemic symptoms, right heart catheterization (RHC) findings and the VECTRA-DA score served as a measure of treatment response.
Nucleotide deletion in RHCE*cE (907delC) is responsible for a D- - haplotype in Hispanics.
Reid et al., Philadelphia, United States. In Transfusion, 2011
A novel allele of RHCE, RHCE*cE 907delC, silences c and E and in the homozygous state resulting in a D- - phenotype and production of anti-Rh17.
Allele-specific oligonucleotide polymerase chain reaction for the determination of Rh C/c and Rh E/e antigens in thalassaemic patients.
Mahdavi et al., Tehrān, Iran. In Blood Transfus, 2011
Allele-specific oligonucleotide polymerase chain reaction for the determination of Rh C/c and Rh E/e antigens in thalassaemic patients.
Molecular genetics and clinical applications for RH.
Flegel, Bethesda, United States. In Transfus Apher Sci, 2011
The RHD and RHCE genes are strongly homologous.
A novel RHCE*ce 48C, 733G allele with Nucleotide 941C in Exon 7 encodes an altered red blood cell e antigen.
Reid et al., New York City, United States. In Transfusion, 2011
Study identifies a novel allele, RHCE*ce 48C, 733G, 941C, 1006T which is predicted to encode 16Cys, 245Val, 314Ala, and 336CyS and was shown to encode c, V/VS, and an altered expression of e and hrB antigens.
[The molecular basis of RH system and its applications in obstetrics and transfusion medicine].
Moron et al., São Paulo, Brazil. In Rev Assoc Med Bras, 2010
Currently more than 49 antigens were identified with five major antigens D, C, c, E, e. Knowledge of the Rh system's molecular basis, since its first cloning 17 years ago, allowed to understand the mechanism of Rh-negative phenotype and the variants of antigens as RHD and RHCE.
Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.
Flegel et al., In Transfusion, 2010
JAL and JAHK antigens are expressed by Ce and ce and varients of RhCE protein
RHCE*ceAR encodes a partial c (RH4) antigen.
Reid et al., New York City, United States. In Immunohematology, 2009
RHCE*ceAR encodes a partial c (RH4) antigen.
Dolor et al., Rockville, United States. In Unknown Journal, 0001
N-terminal pro-B-type natriuretic peptide (NT-proBNP) showed moderate correlation with right heart catheterization (RHC) hemodynamic measures and a great deal of variability between studies in its diagnostic accuracy and discrimination; however, one good-quality prospective cohort study suggested that biomarker testing with NT-proBNP might be useful in ruling out PAH in patients with symptoms suggestive of PAH who have elevated systolic pulmonary artery pressure (sPAP) by echocardiography.
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