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Calcium channel, voltage-dependent, R type, alpha 1E subunit

T-type low voltage-activated calcium channel that may be involved in neuronal firing [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: RHCE, HAD, OUT, CD45, Tris
Papers on RBE-2
Two sets of amino acids of the domain I of Cav2.3 Ca(2+) channels contribute to their high sensitivity to extracellular protons.
Charnet et al., Montpellier, France. In Pflugers Arch, 2011
identified in the Cav2.3 domain I two sets of amino acids that are responsible of the sensitivity of activation potential (Va) and maximal whole cell conductance (G) to pHo variations
Polymorphisms in CACNA1E and Camk2d are associated with seizure susceptibility of Sprague-Dawley rats.
Hoogland et al., Maastricht, Netherlands. In Epilepsy Res, 2010
Calcium channel voltage-dependent L type alpha 1E subunit (CACNA1E) polymorphisms are associated with individual variability in seizure susceptibility of Sprague-Dawley rats.
Molecular determinant for specific Ca/Ba selectivity profiles of low and high threshold Ca2+ channels.
Charnet et al., Montpellier, France. In J Gen Physiol, 2007
Essential in Ca++ selectivity over other divalent cations, at a conserved EEEE locus
Alpha1E-containing Ca2+ channels are involved in synaptic plasticity.
Schmitz et al., Berlin, Germany. In Proc Natl Acad Sci U S A, 2003
alpha1E-containing voltage-dependent calcium channels (VDCCs) shift the threshold for mossy fiber LTP
Voltage-gated calcium channels in adult rat inferior colliculus neurons.
Morad et al., Washington, D.C., United States. In Neuroscience, 2002
Neurons in the inferior colliculus express Ca(2+) channel alpha(1A), alpha(1B), alpha(1C), alpha(1D), and alpha(1E) subunits.
Transport activity and surface expression of the Na+-Ca2+ exchanger NCX1 are inhibited by the immunosuppressive agent cyclosporin A and by the nonimmunosuppressive agent PSC833.
Rahamimoff et al., Bethesda, United States. In J Biol Chem, 2002
EMBL accession number ) or the rat brain RBE-2 (NCX1.5,
The transport activity of the Na+-Ca2+ exchanger NCX1 expressed in HEK 293 cells is sensitive to covalent modification of intracellular cysteine residues by sulfhydryl reagents.
Rahamimoff et al., Jerusalem, Israel. In J Biol Chem, 2001
Membrane permeable N-ethylmaleimide (NEM) and (2-aminoethyl)methanethiosulfonatehydrobromide (MTSEA) inhibited the rat brain Na(+)-Ca(2+) exchanger RBE-2 (NCX1.5)
Cloning of two isoforms of the rat brain Na(+)-Ca2+ exchanger gene and their functional expression in HeLa cells.
Rahamimoff et al., Jerusalem, Israel. In Febs Lett, 1993
The open reading frame of clone RBE-1 codes for a protein 935 amino acids long, and that of clone RBE-2 codes for a protein 958 amino acids long.
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