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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Low density lipoprotein receptor-related protein associated protein 1

Protein contains putative RNA binding domain. Expressed in response to Pseudomonas syringae infection. Resistance requires silencing of AtRAP suggesting it functions as a negative regulator of plant disease resistance. (from NCBI)
Top mentioned proteins: M VP, CAN, HAD, ACID, V1a
Papers on RAP
LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response.
Gonias et al., Roma, Italy. In Proc Natl Acad Sci U S A, Feb 2016
The antagonists, receptor-associated protein (RAP) and lactoferrin (LF), and LRP1-specific antibody had the entirely opposite effect, promoting inflammatory mediator expression and mimicking LRP1 deletion.
Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways.
Liu et al., Taiwan. In Free Radic Biol Med, Jan 2016
Compared with momordin Ic treatment alone, the autophagy inhibitor 3-methyladenine (3-MA) also can inhibit apoptosis, while autophagy activator rapamycin (RAP) has the opposite effect, and the apoptosis inhibitor ZVAD-fmk also inhibited autophagy induced by momordin Ic.
TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells.
Han et al., Hong Kong, Hong Kong. In J Ethnopharmacol, Jan 2016
AIM OF STUDY: To investigate the molecular mechanism of immunomodulating activities of a reported Astragalus polysaccharide, RAP, which is a hyperbranched heteroglycan with average molecular weight of 1334kDa.
Pathogenic Gut Flora in Patients With Chronic Heart Failure.
Dioguardi et al., Brescia, Italy. In Jacc Heart Fail, Jan 2016
However, the relation between pathogenic gut flora and CHF severity, as well as IP, venous blood congestion as right atrial pressure (RAP), and/or systemic inflammation (C-reactive protein [CRP]), is still unknown.
Randomized, Placebo-Controlled, Double-Blind Pilot Study of D-Cycloserine in Chronic Stroke.
Wolf et al., Atlanta, United States. In Rehabil Res Pract, 2014
We hypothesized that D-cycloserine, when combined with robotic-assisted physiotherapy (RAP), would result in greater gains compared with placebo + RAP in stroke survivors.
Effect of SERCA2a overexpression in the pericardium mediated by the AAV1 gene transfer on rapid atrial pacing in rabbits.
Wulasihan et al., Ürümqi, China. In Genet Mol Res, 2014
To study the effects of overexpression of the sarcoplasmic reticulum ATPase 2a (SERCA2a) gene on the activity and protein expression of SERCA2a after rapid atrial pacing (RAP) in New Zealand white rabbits.
Unveiling the hidden function of long non-coding RNA by identifying its major partner-protein.
Zhu et al., Beijing, China. In Cell Biosci, 2014
Here we review progress of molecular archetypes that lncRNAs execute as guides, scaffolds, or decoys for protein, focusing on advantages, shortcomings and applications of various conventional and emerging technologies to probe lncRNAs and protein interactions, including protein-centric biochemistry approaches such as nRIP and CLIP, and RNA-centric biochemistry approaches such as ChIRP, CHART and RAP.
Roles of Nebulin Family Members in the Heart.
Chen et al., Milano, Italy. In Circ J, 2014
The members of the nebulin protein family, including nebulin, nebulette, LASP-1, LASP-2, and N-RAP, contain various numbers of nebulin repeats and bind to actin, but are otherwise heterogeneous with regard to size, expression pattern, and function.
Ranibizumab and aflibercept for the treatment of wet age-related macular degeneration.
Abdollahi et al., Karaj, Iran. In Expert Opin Biol Ther, 2014
EXPERT OPINION: Ranibizumab and aflibercept are effective for the treatment of wet AMD including those with retinal angiomatous proliferation (RAP) and CNV unresponsive to other anti-VEGF agents.
Regional Acceleratory Phenomenon.
Verna, In Front Oral Biol, 2014
The regional acceleratory phenomenon (RAP) is a tissue reaction to a noxious stimulus that increases the healing capacities of the affected tissues.
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.
Lander et al., Cambridge, United States. In Cell, 2014
To identify these contacts, we developed a method based on RNA antisense purification to systematically map RNA-RNA interactions (RAP-RNA) and applied it to investigate two ncRNAs implicated in RNA processing: U1 small nuclear RNA, a component of the spliceosome, and Malat1, a large ncRNA that localizes to nuclear speckles.
Comprehensive analysis of RNA-protein interactions by high-throughput sequencing-RNA affinity profiling.
Lis et al., Ithaca, United States. In Nat Methods, 2014
We have developed a high-throughput sequencing-RNA affinity profiling (HiTS-RAP) assay by adapting a high-throughput DNA sequencer to quantify the binding of fluorescently labeled protein to millions of RNAs anchored to sequenced cDNA templates.
Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis.
Kumar et al., Cambridge, United States. In Nat Med, 2014
ACE-536, or its mouse version RAP-536, produced rapid and robust increases in erythrocyte numbers in multiple species under basal conditions and reduced or prevented anemia in murine models.
An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.
Moura et al., Paris, France. In Nat Med, 2014
We report that RAP-011, an activin receptor IIA (ActRIIA) ligand trap, improved ineffective erythropoiesis, corrected anemia and limited iron overload in a mouse model of β-thalassemia intermedia.
Proton-detected solid-state NMR spectroscopy at aliphatic sites: application to crystalline systems.
Reif et al., München, Germany. In Acc Chem Res, 2013
Our labeling scheme is based on u-[(2)H,(13)C]-glucose and 5-25% H2O (95-75% D2O) in the M9 bacterial growth medium, known as RAP (reduced adjoining protonation).
Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms.
Daugherty et al., Beijing, China. In Atherosclerosis, 2012
RAP deficiency attenuated atherosclerosis without influencing abdominal aortic aneurysms in hypercholesterolemic mice infused with angiotensin II.
Lack of interaction between LRP1 and A2M polymorphisms for the risk of Alzheimer disease.
Zappia et al., Catania, Italy. In Neurosci Lett, 2010
LRP1-C/T, A2M-Ile/Val and APOE-epsilon 2/epsilon 3/epsilon 4 polymorphisms are associated with AD.
Receptor-associated protein interacts with amyloid-beta peptide and promotes its cellular uptake.
Bu et al., Saint Louis, United States. In J Biol Chem, 2009
Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta.
LRP-associated protein gene (LRPAP1) and susceptibility to degenerative dementia.
Mittal et al., Lucknow, India. In Genes Brain Behav, 2008
Our study suggests that LRPAP1-D and APOE E4 alleles significantly increase the susceptibility to degenerative dementias.
Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.
Borchelt et al., Gainesville, United States. In Plos One, 2007
Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice
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