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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Amine oxidase, copper containing 2

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, V1a, IL-8, ACID
Papers on RAO
Tamoxifen as a new therapeutic tool for neutrophilic lung inflammation.
Morán et al., Valdivia, Chile. In Respirology, Jan 2016
Equine recurrent airway obstruction (RAO) is a naturally occurring neutrophilic condition, closely related with human asthma.
Secretoglobin and Transferrin Expression in Bronchoalveolar Lavage Fluid of Horses with Chronic Respiratory Disease.
Raskin et al., West Lafayette, United States. In J Vet Intern Med, Nov 2015
BACKGROUND: Lower expression of secretoglobin and transferrin has been found in the bronchoalveolar lavage fluid (BALF) of a small number of horses with experimentally induced signs of recurrent airway obstruction (RAO) compared to healthy controls.
Exenatide Regulates Cerebral Glucose Metabolism in Brain Areas Associated With Glucose Homeostasis and Reward System.
Gastaldelli et al., Pisa, Italy. In Diabetes, Oct 2015
The cerebral glucose metabolic rate (CMRglu) was measured by positron emission tomography after an injection of [(18)F]2-fluoro-2-deoxy-d-glucose before the OGTT, and the rate of glucose absorption (RaO) and disposal was assessed using stable isotope tracers.
Genetics of upper and lower airway diseases in the horse.
Marti et al., Bern, Switzerland. In Equine Vet J, Jul 2015
Genetic predispositions for guttural pouch tympany, recurrent laryngeal neuropathy and recurrent airway obstruction (RAO) are well documented.
Expression of surface platelet receptors (CD62P and CD41/61) in horses with recurrent airway obstruction (RAO).
Pliszczak-Krol et al., Wrocław, Poland. In Vet Immunol Immunopathol, Apr 2015
Recurrent airway obstruction (RAO) is an allergic disease of horses similar to human asthma, which is characterized by airway inflammation and activation of neutrophils, lymphocytes and platelets.
The prevalence of a false-positive myocardial perfusion stress SPET test in a skinny patient, induced by projection truncation.
Georgoulias et al., Lárisa, Greece. In Hell J Nucl Med, 2015
Projection images were obtained from 45° RAO to 45° LPO position, in step and shoot mode (60 projections, 30sec per projection; matrix 64×64 and zoom 1.3).
Metalloproteinases and Their Tissue Inhibitors in Comparison between Different Chronic Pneumopathies in the Horse.
Gehlen et al., Berlin, Germany. In Mediators Inflamm, 2014
Using a scoring system, 61 horses were classified controls as free of respiratory disease (n = 15), recurrent airway obstruction (RAO, n = 17), inflammatory airway disease (IAD, n = 18), or chronic interstitial pneumopathy (CIP, n = 11).
Differential Gene Expression Profiles and Selected Cytokine Protein Analysis of Mediastinal Lymph Nodes of Horses with Chronic Recurrent Airway Obstruction (RAO) Support an Interleukin-17 Immune Response.
Ainsworth et al., Ithaca, United States. In Plos One, 2014
Recurrent airway obstruction (RAO) is a pulmonary inflammatory condition that afflicts certain mature horses exposed to organic dust particulates in hay.
Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.
Gerber et al., Bern, Switzerland. In Plos One, 2014
Recurrent airway obstruction (RAO) is a common and potentially debilitating lower airway disease in horses, which shares many similarities with human asthma.
Diagnostic ramifications of ocular vascular occlusion as a first thrombotic event associated with factor V Leiden and prothrombin gene heterozygosity.
Wang et al., Cincinnati, United States. In Clin Ophthalmol, 2014
Of the 29 cases, 16 had central retinal vein occlusion (CRVO), 2 branch retinal vein occlusion (BRVO), 5 nonarteritic anterior ischemic optic neuropathy (NA-AION), 3 retinal artery occlusion (RAO), 2 amaurosis fugax (AF), and 1 had both CRVO and RAO.
Circulating immune complexes and markers of systemic inflammation in RAO-affected horses.
Kubiak et al., In Pol J Vet Sci, 2013
Horses were divided into two groups: 7 horses were not affected by any respiratory problem (control group) and 7 horses had a history of recurrent airway obstruction (RAO) (study group).
Archaic human genomics.
Disotell, New York City, United States. In Am J Phys Anthropol, 2011
A contrasting model positing a single origin, in Africa, of anatomically modern H. sapiens with some populations later migrating out of Africa and replacing the local archaic populations throughout the world with complete replacement became known as the recent African origin (RAO) model.
IgE in horses: occurrence in health and disease.
Wagner, Ithaca, United States. In Vet Immunol Immunopathol, 2009
The causing role of IgE in other diseases such as recurrent airway obstruction (RAO) still remains controversial.
The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.
Elima et al., Turku, Finland. In Cell Mol Life Sci, 2009
AOC2 mRNA is expressed in many tissues, however, the only tissues with detectable AOC2-like enzyme activity is found in the eye.
[Genetics of recurrent airway obstruction (RAO)].
Leeb et al., Bern, Switzerland. In Dtsch Tierarztl Wochenschr, 2008
Recurrent airway obstruction (RAO) is a multifactorial and polygenic disease.
Molecular mechanism of enzymatic allene oxide cyclization in plants.
Pollmann et al., Bochum, Germany. In Plant Physiol Biochem, 2008
In this context, we will discuss the crystal structure of AOC2 of Arabidopsis thaliana with respect to putative binding sites of the instable substrate, 12,13-epoxy-9(Z),11,15(Z)-octadecatrienoic acid (12,13-EOT), as well as possible intermolecular rearrangements during the cyclization reaction.
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