Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion.
Szeged, Hungary. In J Headache Pain, 2014
We investigated changes of mitogen-activated protein kinases (MAPKs as ERK1/2, p38 and SAPK/JNK), NF-κB, CaMKII and DREAM, in addition to calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1) in the TG, with immunohistochemistry and Western blot at 2 and 10 days post-CFA injection.
CGRP receptor antagonism and migraine therapy.
Lund, Sweden. In Curr Protein Pept Sci, 2013
The CGRP receptor consists of a complex of calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1) and receptor component protein (RCP).
Ectodomain structures of the CGRP and AM receptors.
Yokohama, Japan. In Curr Protein Pept Sci, 2013
Receptor activity-modifying proteins (RAMPs) 1-3, which are classified as type I transmembrane proteins, serve as the partner proteins of several family B GPCRs for physiologically active peptides, including the calcitonin receptor- like receptor (CLR).