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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Retinoic acid induced 2

RAI2, retinoic acid-induced 2
Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this retinoic acid-induced gene has not yet been determined but it may play a role in development. The chromosomal location of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked mental retardation, oral-facial-digital syndrome, and Fried syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] (from NCBI)
Top mentioned proteins: ACID, RbAp46, POLYMERASE, fibrillin-1, Scmh1
Papers on RAI2
Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2.
Wikman et al., Hamburg, Germany. In Cancer Discov, May 2015
Here, we used the presence of disseminated tumor cells (DTC) in the bone marrow to define patients with early disseminated breast cancer and identified low retinoic acid-induced 2 (RAI2) expression to be significantly associated with DTC status.
RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression.
Kang et al., Princeton, United States. In Cancer Discov, May 2015
In this issue of Cancer Discovery, Werner and colleagues report on the discovery of retinoic acid-induced 2 (RAI2) as a differentiation factor that suppresses early metastatic spread of estrogen receptor-positive breast cancer.
Identification of a microdeletion at Xp22.13 in a Taiwanese family presenting with Nance-Horan syndrome.
Chen et al., Taiwan. In J Hum Genet, 2011
The deleted region encompasses the REPS2, NHS, SCML1 and RAI2 genes, and was transmitted from their carrier mother who presented only mild cataract.
Refinement of the X-linked cataract locus (CXN) and gene analysis for CXN and Nance-Horan syndrome (NHS).
Hardcastle et al., London, United Kingdom. In Ophthalmic Genet, 2004
Two known genes (RAI2 and RBBP7) and a novel gene (TL1) were screened for mutations within an affected male from the CXN family and an NHS family by direct sequencing of coding exons and intron- exon splice sites.
Organization and annotation of the Xcat critical region: elimination of seven positional candidate genes.
Stambolian et al., Philadelphia, United States. In Genomics, 2004
The coding regions of the seven known genes within this area (Rai2, Rbbp7, Ctps2, Calb3, Grpr, Reps2, and Syap1) were sequenced in Xcat mice and no mutations were detected.
Exclusion of RAI2 as the causative gene for Nance-Horan syndrome.
Toutain et al., Cambridge, United Kingdom. In Hum Genet, 1999
We previously identified a human homologue of a mouse retinoic-acid-induced gene (RAI2) within the NHS critical flanking interval and have tested the gene as a candidate for Nance-Horan syndrome in nine NHS-affected families.
Identification and characterization of the human homologue (RAI2) of a mouse retinoic acid-induced gene in Xp22.
Trump et al., Cambridge, United Kingdom. In Genomics, 1999
Further investigation of predicted exons from PAC clone 389A20 led to the identification of a single-exon gene, designated RAI2 (retinoic acid-induced 2).
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