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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

PSD1 Psd1p

PSD1, EFA6, Psd1p, EFA6A, exchange factor for ARF6
Top mentioned proteins: ARF6, CAN, Actin, V1a, p16
Papers on PSD1
VID22 is required for transcriptional activation of the PSD2 gene in the yeast Saccharomyces cerevisiae.
Kuge et al., Fukuoka, Japan. In Biochem J, Jan 2016
PSD1 null (psd1Δ) and PSD2 null (psd2Δ) mutants are viable in a synthetic minimal medium, but a psd1Δ psd2Δ double mutant exhibits Etn auxotrophy, which is incorporated into PE through the CDP-Etn pathway.
Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.
Nakayama et al., Kyoto, Japan. In J Biochem, Oct 2015
We further show that EFA6 (exchange factor for Arf6) activates not only Arf6 but also Arf1 in the cell.
Lipid Biosynthetic Genes Affect Candida albicans Extracellular Vesicle Morphology, Cargo, and Immunostimulatory Properties.
Casadevall et al., New York City, United States. In Eukaryot Cell, Aug 2015
The genes encoding phosphatidylserine synthase (CHO1) and phosphatidylserine decarboxylase (PSD1 and PSD2) are Candida albicans genes involved in phospholipid biosynthesis, and mutations in these genes affect mitochondrial function, cell wall thickness, and virulence in mice.
Chryseobacterium solani sp. nov., isolated from field-grown eggplant rhizosphere soil.
Yi et al., South Korea. In Int J Syst Evol Microbiol, Aug 2015
Based on 16S rRNA gene sequence comparisons, strain THG-EP9T had closest similarity with Chryseobacterium ginsenosidimutans THG 15T (97.3 % 16S rRNA gene sequence similarity), Chryseobacterium soldanellicola PSD1-4T (97.2%),
Phosphatidylserine decarboxylase 1 autocatalysis and function does not require a mitochondrial-specific factor.
Claypool et al., Baltimore, United States. In J Biol Chem, Jun 2015
The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p).
Arf6 guanine nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth.
Yamauchi et al., Tokyo, Japan. In J Biol Chem, 2015
Cytohesin-2 is a guanine nucleotide exchange factor for Arf6, an Arf family molecular switch protein, controlling cell morphological changes such as neuritogenesis.
Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis.
Kanaho et al., Tsukuba, Japan. In Sci Rep, 2014
Of the Arf6-specific guanine nucleotide exchange factors, EFA6A, EFA6B, and EFA6D specifically interact with Dyn2.
A Yeast Mutant Deleted of GPH1 Bears Defects in Lipid Metabolism.
Daum et al., Graz, Austria. In Plos One, 2014
In a previous study we demonstrated up-regulation of the yeast GPH1 gene under conditions of phosphatidylethanolamine (PE) depletion caused by deletion of the mitochondrial (M) phosphatidylserine decarboxylase 1 (PSD1) (Gsell et al., 2013, PLoS One.
Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6).
Kanamarlapudi, Swansea, United Kingdom. In J Biol Chem, 2014
The exchange factor for ARF6 (EFA6) R has been identified as a biomarker for ovarian cancer.
The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration.
Goldfinger et al., Philadelphia, United States. In Biochem Biophys Res Commun, 2014
RLIP76 harbors docking sites for many proteins, and we have found that it interacts with ARNO, a guanine nucleotide exchange factor for Arf6, and that RLIP76 regulates activation of Rac1 via Arf6, and regulates cell spreading and migration in an ARNO and Arf6-dependent manner.
Aberrant methylation of PSD disturbs Rac1-mediated immune responses governing neutrophil chemotaxis and apoptosis in ulcerative colitis-associated carcinogenesis.
Konishi et al., Saitama, Japan. In Int J Oncol, 2012
Aberrant methylation of PSD occurs in UC-associated colorectal mucosa, enabling circumvention of Rac1 immune responses governing neutrophil chemotaxis and apoptosis, and plays a pivotal role in the mechanisms underlying UC-associated carcinogenesis.
Aberrant methylation of the Pleckstrin and Sec7 domain-containing gene is implicated in ulcerative colitis-associated carcinogenesis through its inhibitory effect on apoptosis.
Konishi et al., Saitama, Japan. In Int J Oncol, 2012
Both levels of accumulation of F-actin and apoptosis were significantly decreased in specimens from UC patients with PSD methylation compared to those without PSD methylation.
From cradle to twilight: the carboxyl terminus directs the fate of the A(2A)-adenosine receptor.
Freissmuth et al., Vienna, Austria. In Biochim Biophys Acta, 2011
The list includes the deubiquinating enzyme USP4, α-actinin, the guanine nucleotide exchange factor for ARF6 ARNO, translin-X-associated protein, calmodulin, the neuronal calcium binding protein NECAB2 and the synapse associated protein SAP102.
The myelin sheath aqueous layers improve the membrane properties of simulated chronic demyelinating neuropathies.
Daskalova et al., Sofia, Bulgaria. In J Integr Neurosci, 2011
Four degrees of systematic paranodal demyelinations (two mild demyelinations termed PSD1 and PSD2, without/with aqueous layers respectively, and two severe demyelinations termed PSD3 and PSD4, with/without aqueous layers, respectively) are simulated using our previous multi-layered model of human motor nerve fibre.
EFA6A encodes two isoforms with distinct biological activities in neuronal cells.
Talarico et al., Milano, Italy. In J Cell Sci, 2009
EFA6A could participate in neuronal morphogenesis through the regulated expression of two functionally distinct isoforms.
Phosphatidylethanolamine is required for normal cell morphology and cytokinesis in the fission yeast Schizosaccharomyces pombe.
Marcus et al., Tuscaloosa, United States. In Eukaryot Cell, 2009
Psd1, psd2, and psd3, encoding phosphatidylserine decarboxylases catalyze the phosphatidylserine to phosphatidylethanolamine.
Localization of EFA6A, a guanine nucleotide exchange factor for ARF6, in spermatogenic cells of testes of adult mice.
Kondo et al., Akita, Japan. In J Mol Histol, 2009
Results showed that EFA6A was first shown localized intensely in nuclei of spermatocytes of adult testes and suggested a possible involvement of EFA6A-ARF6 signaling in the karyokinesis and cytokinesis.
The EFA6 family: guanine nucleotide exchange factors for ADP ribosylation factor 6 at neuronal synapses.
Sakagami, In Tohoku J Exp Med, 2008
The EFA6 family is the first member that was identified to be a specific GEF for ARF6 and comprises four structurally related polypeptides (EFA6A, EFA6B, EFA6C and EFA6D).
New perspectives on the regulation of intermembrane glycerophospholipid traffic.
Voelker, Denver, United States. In J Lipid Res, 2003
PtdSer is transported to the mitochondria in mammalian cells and yeast, and decarboxylated by PtdSer decarboxylase 1 (Psd1p) to form PtdEtn.
Phosphatidylserine decarboxylase.
Voelker, Denver, United States. In Biochim Biophys Acta, 1997
Phosphatidylserine decarboxylase (PSD) is an important enzyme in the synthesis of phosphatidylethanolamine in both prokaryotes and eukaryotes.
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