Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study
In Diabetes, 2007
... The PGC-1α, actin, IR, Pbx1, Syp, SHP1, PTP1B, G6Pase, and PEPCK antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Leptin signalling pathways in hypothalamic neurons.
Seoul, South Korea. In Cell Mol Life Sci, Feb 2016
These include SOCS3, tyrosine phosphatase PTP1B, and inflammatory signaling pathways such as IKK-NFκB and JNK signaling, and ER stress-mitochondrial signaling.
The Molecular Mechanisms and Rational Design of Anti-Diabetic Vanadium Compounds.
Beijing, China. In Curr Top Med Chem, Dec 2015
It has been revealed that vanadium compounds exert insulin enhancement effects and cell protection via a multiple mechanism involving inhibition of PTP1B, activation of PPARs- AMPK signaling, regulation of unfolded protein responses (UPRs), and stimulation of antioxidant enzymes, while vanadium-induced oxidative stress and inflammatory response could primarily be attributed to vanadium toxicity.
Potential Bioactive Compounds from Seaweed for Diabetes Management.
Kuala Lumpur, Malaysia. In Mar Drugs, Aug 2015
In this review, we discussed the diversity of seaweed composition and bioactive compounds which are potentially useful in preventing or managing T2DM by targeting various pharmacologically relevant routes including inhibition of enzymes such as α-glucosidase, α-amylase, lipase, aldose reductase, protein tyrosine phosphatase 1B (PTP1B) and dipeptidyl-peptidase-4 (DPP-4).