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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Protein arginine methyltransferase 2

Top mentioned proteins: Protein-Arginine N-Methyltransferase, CARM1, PRMT3, Histone, PRMT5
Papers on PRMT2
Quantification of Arginine and Its Methylated Derivatives in Plasma by High-Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS).
Haymond et al., Chicago, United States. In Methods Mol Biol, Dec 2015
Arginine is methylated through the activity of protein arginine methyltransferases (PRMT1 and PRMT2), to form asymmetrical dimethylarginine (ADMA) and symmetrical dimethylarginine (SDMA).
Synthesis, Anticancer Activity, and Genome Profiling of Thiazolo Arene Ruthenium Complexes.
Therrien et al., Cluj-Napoca / Kolozsvár, Romania. In J Med Chem, Dec 2015
New activated molecules such as FAS, ZMAT3, PRMT2, BBC3/PUMA, and PDCD4, whose overexpressions are correlated with overcoming resistance to cisplatin therapy, were also identified as potential targets.
Arginine methyltransferases mediate an epigenetic ovarian response to endometriosis.
De La Fuente et al., Grand Rapids, United States. In Reproduction, Oct 2015
Ingenuity Pathway Analysis indicated that transcripts for chromatin-remodeling enzymes associated with reproductive system disease and cancer development were abnormally regulated, most prominently the arginine methyltransferases CARM1, PRMT2, and PRMT8.
Polymorphisms in DCDC2 and S100B associate with developmental dyslexia.
Kere et al., Huddinge, Sweden. In J Hum Genet, Jul 2015
We aimed at discovering single nucleotide variation present in known and new candidate genes for developmental dyslexia: CYP19A1, DCDC2, DIP2A, DYX1C1, GCFC2 (also known as C2orf3), KIAA0319, MRPL19, PCNT, PRMT2, ROBO1 and S100B.
A novel BLAST-Based Relative Distance (BBRD) method can effectively group members of protein arginine methyltransferases and suggest their evolutionary relationship.
Li et al., T'ai-chung-shih, Taiwan. In Mol Phylogenet Evol, Mar 2015
The tree placed the uncharacterized PRMT9 with PRMT7 in the same clade, outside of all the Type I PRMTs including PRMT1 and its vertebrate paralogue PRMT8, PRMT3, PRMT6, PRMT2 and PRMT4.
LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.
Garabedian et al., New York City, United States. In Plos One, 2014
To probe for this mechanism, we surveyed the expression of a host of chromatin-modifying enzymes and found that Protein Arginine Methyltransferase 2 (PRMT2) was reduced in high compared to normal glucose conditions.
Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein.
Wen et al., Hengyang, China. In Oncogene, 2014
Human protein arginine N-methyltransferase 2 (PRMT2, HRMT1L1) is a protein that belongs to the arginine methyltransferase family, and it has diverse roles in transcriptional regulation through different mechanisms depending on its binding partners.
PRMT2 and RORγ expression are associated with breast cancer survival outcomes.
Muscat et al., Brisbane, Australia. In Mol Endocrinol, 2014
However, the role of PRMT2-dependent signaling in breast cancer remains obscure.
Role of PRMTs in cancer: Could minor isoforms be leaving a mark?
Côté et al., Ottawa, Canada. In World J Biol Chem, 2014
Specifically, PRMT1, PRMT2, CARM1 and PRMT7 have been shown to have alternative isoforms and others may be currently unrealized.
Identification of splice variants, expression analysis and single nucleotide polymorphisms of the PRMT2 gene in dairy cattle.
Liu et al., China. In Gene, 2014
Protein arginine N-methyltransferase 2 (PRMT2), also named HRMT1L1, belongs to the Bovine Protein arginine N-methyltransferase (PRMT) genes which are involved in the immune response.
Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1.
Li et al., Beijing, China. In Genes Dev, 2014
In vivo functional studies suggest that Spindlin1 activates Wnt/β-catenin signaling downstream from protein arginine methyltransferase 2 (PRMT2) and the MLL complex, which together are capable of generating a specific H3 "K4me3-R8me2a" pattern.
DNA methylation-specific multiplex assays for body fluid identification.
Lee et al., Seoul, South Korea. In Int J Legal Med, 2013
After confirming the stability of the body fluid-specific DNA methylation profile over time, two different multiplex PCR systems were constructed using methylation-sensitive restriction enzyme PCR and methylation SNaPshot, in order to analyze the methylation status of specific CpG sites from the USP49, DACT1, PRMT2, and PFN3 tDMRs.
Differential mRNA expression levels of human histone-modifying enzymes in normal karyotype B cell pediatric acute lymphoblastic leukemia.
Pan et al., Suzhou, China. In Int J Mol Sci, 2012
Eleven genes were upregulated in pediatric ALL, including the histone deacetylases HDAC2 and PAK1, and seven genes were downregulated, including PRMT2 and the putative tumor suppressor EP300.
Evolutionarily conserved protein arginine methyltransferases in non-mammalian animal systems.
Li et al., T'ai-chung-shih, Taiwan. In Febs J, 2012
We show the conservation of the most typical type I PRMT1 and type II PRMT5 in all of the species examined, the wide yet different distribution of PRMT3, 4 and 7 in non-mammalian animals, the vertebrate-restricted distribution of PRMT8 and the special reptile/avian-deficient distribution of PRMT2 and 6.
Identification and characterization of novel spliced variants of PRMT2 in breast carcinoma.
Wen et al., Hengyang, China. In Febs J, 2012
characterization of 3 PRMT2 splice variants (PRMT2alpha, PRMT2beta, and PRMT2gamma) from breast cancer; these variants bind to ERalpha in vitro/in vivo; overall PRMT2 expression is upregulated in breast cancer and associated w/ ERalpha positivity
Identification and expression analysis of a novel transcript of the human PRMT2 gene resulted from alternative polyadenylation in breast cancer.
Wen et al., Hengyang, China. In Gene, 2011
Data suggest that post-transcriptional processing mechanism as alternative polyadenylation and splicing may play a crucial role in regulating human PRMT2 gene expression.
Prmt2 regulates the lipopolysaccharide-induced responses in lungs and macrophages.
Hérault et al., Illkirch-Graffenstaden, France. In J Immunol, 2011
Prmt2 is a new member of the NF-kappaB pathway controlling lipopolysaccharide (LPS)-induced inflammatory lung and macrophage responses in a dosage-dependent manner.
A protein arginine N-methyltransferase 1 (PRMT1) and 2 heteromeric interaction increases PRMT1 enzymatic activity.
Frankel et al., Vancouver, Canada. In Biochemistry, 2011
the SH3 domain may mediate an interaction between PRMT1 and -2 in a methylation-dependent fashion
The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome.
Herault et al., Illkirch-Graffenstaden, France. In Behav Brain Res, 2011
this study suggesting that the Cstb-Prmt2 region is not playing a major role in locomotor and cognitive deficits found in mice model of Down syndrome.
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