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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Plexin D1

plexin D1, PLXND1
Top mentioned proteins: V1a, vascular endothelial growth factor, Neuropilin-1, CAN, Akt
Papers on plexin D1
PlexinD1 is required for proper patterning of the periocular vascular network and for the establishment of corneal avascularity during avian ocular development.
Lwigale et al., Houston, United States. In Dev Biol, Feb 2016
Although signaling through PlexinD1 underlies various vascular patterning events during embryonic development, its role during the formation of the periocular vascular network is yet to be determined.
Patterning mechanisms of the sub-intestinal venous plexus in zebrafish.
Childs et al., Calgary, Canada. In Dev Biol, Feb 2016
We applied our analysis of SIVP development to obd mutants that have a mutation in the guidance receptor PlexinD1.
Filamin A interacting protein plays a role in proper positioning of callosal projection neurons in the cortex.
Sato et al., Fukui, Japan. In Neurosci Lett, Jan 2016
The positioning of the callosal projection neurons, especially those expressing Plxnd1, in the superficial layer of the cortex is disturbed in these mice, which suggests that FILIP is a key molecule that links callosal projections to the pathogenesis of brain disorders.
Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor.
Zhang et al., Linyi, China. In J Biosci, Dec 2015
Using neutralizing antibody against Sema4A receptor, PlexinD1, we found that endogenous Sema4A signalling in SSc fibroblast was through PlexinD1 receptor.
Plexin-D1/Semaphorin 3E pathway may contribute to dysregulation of vascular tone control and defective angiogenesis in systemic sclerosis.
Guiducci et al., Florence, Italy. In Arthritis Res Ther, 2014
The aim of the present study was to investigate whether in systemic sclerosis (SSc) Plexin-D1/Sema3E axis could be involved in the dysregulation of vascular tone control and angiogenesis.
To die or not to die: Sema3E rules the game.
Rehman et al., Torino, Italy. In Cancer Cell, 2013
Sema3E, a ligand for PlexinD1, controls angiogenesis and promotes cancer invasion and metastasis.
Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers.
Mann et al., Marseille, France. In Cancer Cell, 2013
Here, we demonstrate that the Semaphorin 3E (Sema3E) regulates tumor cell survival by suppressing an apoptotic pathway triggered by the Plexin D1 dependence receptor.
Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity.
Minamino et al., Chiba, Japan. In Cell Metab, 2013
Expression of Sema3E and its receptor plexinD1 was upregulated in the adipose tissue of a mouse model of dietary obesity.
The Semaphorin 3E/PlexinD1 axis regulates macrophage inflammation in obesity.
Moore et al., New York City, United States. In Cell Metab, 2013
Increased accumulation of adipose tissue macrophages in obesity propagates chronic inflammation that is closely associated with insulin resistance and type 2 diabetes.
The role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development.
Gu et al., Boston, United States. In Semin Cell Dev Biol, 2013
However, unlike other Sema3 family proteins, Sema3E directly binds to Plexin-D1 without neuropilins.
Semaphorin 3E-Plexin-D1 signaling controls pathway-specific synapse formation in the striatum.
Gu et al., Boston, United States. In Nat Neurosci, 2012
This study demonstrated that Sema3E and Plexin-D1 specify the degree of glutamatergic connectivity between a specific source and target in the complex circuitry of the basal ganglia.
Plexin D1: new potential biomarker for cervical cancer.
Hampson et al., Riyadh, Saudi Arabia. In J Immunoassay Immunochem, 2011
Strong expression of plexD1 was detected in endothelial cells of cervical cancer samples, yet no expression was seen in endothelial cells of normal cervical tissues, which suggests a potential role of PlexD1 in cervical cancer-associated angiogenesis
Phosphatidylinositol-4-phosphate 5-kinase and GEP100/Brag2 protein mediate antiangiogenic signaling by semaphorin 3E-plexin-D1 through Arf6 protein.
Gutkind et al., Bethesda, United States. In J Biol Chem, 2011
a novel phospholipid-regulated antiangiogenic signaling pathway whereby Sema3E activates Arf6 through Plexin-D1 and consequently controls integrin-mediated endothelial cell attachment to the extracellular matrix and migration.
Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism.
Gu et al., Boston, United States. In Genes Dev, 2011
a novel role of Sema3E-Plexin-D1 function in modulating angiogenesis via a VEGF-induced feedback mechanism
Biology and function of neuroimmune semaphorins 4A and 4D.
Chapoval et al., Baltimore, United States. In Immunol Res, 2011
It is known that Sema4A has three functional receptors, namely Plexin D1, Plexin B1, and Tim-2, whereas Sema4D binds to Plexin B1 and CD72.
Diverse functions for the semaphorin receptor PlexinD1 in development and disease.
Torres-Vázquez et al., New York City, United States. In Dev Biol, 2011
Until recently, little was known about the function of PlexinD1, the sole member of the vertebrate-specific PlexinD (PlxnD1) subfamily.
Sema3E/plexin-D1 mediated epithelial-to-mesenchymal transition in ovarian endometrioid cancer.
Huang et al., Taipei, Taiwan. In Plos One, 2010
analysis of Sema3E/plexin-D1 mediated epithelial-to-mesenchymal transition in ovarian endometrioid cancer
Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition.
Arber et al., Basel, Switzerland. In Nature, 2009
a recognition system involving expression of class 3 semaphorin Sema3e by selected motor neuron pools, and its high-affinity receptor plexin D1 by proprioceptive sensory neurons, is a critical determinant of synaptic specificity in sensory-motor circuits
Guidance of vascular and neural network formation.
Carmeliet et al., Paris, France. In Curr Opin Neurobiol, 2005
In particular, Semaphorin3E and its receptor plexinD1 in addition to the Netrin receptor UNC5B have recently been shown to direct endothelial tip cell navigation.
Semaphorins guide PerPlexeD endothelial cells.
Deutsch, Bern, Switzerland. In Dev Cell, 2004
Abrogation of the endothelial cell-specific semaphorin receptor PlexinD1 in zebrafish and mouse reveals semaphorin functions selectively affecting the cardiovascular system.
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