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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Phosphatidylinositol-4-phosphate 5-kinase-like 1

PIP5KL1, Phosphatidylinositol-4-phosphate 5-kinase-like 1, PIPKH
PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 [PubMed 14701839]).[supplied by OMIM, Jun 2009] (from NCBI)
Top mentioned proteins: POLYMERASE, CAN, Bax, NET, Actin
Papers on PIP5KL1
Overexpression of PIP5KL1 suppresses cell proliferation and migration in human gastric cancer cells.
Huang et al., Beijing, China. In Mol Biol Rep, 2010
These studies indicate a functional negative correlation between elevated levels of PIP5KL1 and the development of human gastric cancer.
Overexpression of PIP5KL1 suppresses the growth of human cervical cancer cells in vitro and in vivo.
Huang et al., Beijing, China. In Cell Biol Int, 2010
PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase-like 1), the fourth member of PIP5Ks (phosphatidylinositol-4-phosphate 5-kinases) type I, acts as a scaffold for localization and activation of PIP5Ks, which in turn regulate numerous cellular processes.
Cell-based screening and validation of human novel genes associated with cell viability.
Ma et al., Beijing, China. In J Biomol Screen, 2006
A subsequent fluorescence-based assay revealed that 4 of the 39 genes (PIP5KL1, OLFM1, RNF122, FAM26B) were associated with cell viability.
Identification and characterization of a phosphoinositide phosphate kinase homolog.
Cantley et al., Boston, United States. In J Biol Chem, 2004
PIPKH acts as a scaffold to localize and regulate type I PI(4)P 5-kinases and the synthesis of PI(3,4,5)P(3)
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