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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Phosphatidylinositol 4-kinase, catalytic, beta

PI4Kbeta, PI4K92, PtdIns 4-kinase beta
phosphorylates phosphatidylinositol (PtdIns) at the D4 position of the inositol ring; may play a role in neuronal differentiation and maturation [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: NCS-1, CAN, ACID, STEP, HAD
Papers on PI4Kbeta
PI4K-beta and MKNK1 are regulators of hepatitis C virus IRES-dependent translation.
Thoma et al., Strasbourg, France. In Sci Rep, 2014
Cellular translation is down-regulated by host antiviral responses.
The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ.
Derisi et al., San Francisco, United States. In J Virol, 2012
The 3A protein of picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIbeta.
Phosphatidylinositol 4-kinase IIIβ is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry.
Jiang et al., Beijing, China. In J Biol Chem, 2012
Phosphatidylinositol 4-kinase IIIbeta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry.
ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites.
Taniguchi et al., Japan. In Embo J, 2012
results indicate that a viral protein/ACBD3/PI4KB complex is formed to synthesize PI4P at the AiV RNA replication sites and plays an essential role in viral RNA replication
ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication.
Chung et al., Beijing, China. In Plos One, 2011
During authentic HCV infection, PI4P plays an integral role in virus replication; the vesicular transport proteins ARF1 and GBF1 colocalized with PI4KIIIbeta and were both required for HCV replication.
The lipid kinase PI4KIIIβ and the eEF1A2 oncogene co-operate to disrupt three-dimensional in vitro acinar morphogenesis.
Lee et al., Ottawa, Canada. In Exp Cell Res, 2011
The PI4KIIIbeta likely plays an important role in mammary neoplasia and acinar development.
Role of neuronal Ca2+-sensor proteins in Golgi-cell-surface membrane traffic.
Kreutz et al., Magdeburg, Germany. In Biochem Soc Trans, 2010
The activity of PI4Kbeta (phosphoinositide 4-kinase IIIbeta) at the Golgi membrane is a first mandatory step in this process.
TRAPPII is required for cleavage furrow ingression and localization of Rab11 in dividing male meiotic cells of Drosophila.
Fuller et al., Stanford, United States. In J Cell Sci, 2010
bru also genetically interacts with four wheel drive (fwd), which encodes a PI4Kbeta, such that double mutants exhibit enhanced failure of male meiotic cytokinesis.
Frequenin/NCS-1 and the Ca2+-channel alpha1-subunit co-regulate synaptic transmission and nerve-terminal growth.
Atwood et al., Toronto, Canada. In J Cell Sci, 2009
We hypothesized that Frq either modulates Ca(2+) channels, or that it regulates the PI4Kbeta pathway as described in other organisms.
Type II phosphatidylinositol 4-kinases promote Listeria monocytogenes entry into target cells.
Cossart et al., Paris, France. In Cell Microbiol, 2007
PI4KIIalpha or PI4KIIbeta knockdown, but not type III PI4Kbeta knockdown, inhibits Listeria internalization.
Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta.
Burgoyne et al., Liverpool, United Kingdom. In Traffic, 2007
To investigate potential functional differences between the human ARF proteins, we have examined the localization of all human ARF isoforms and their interactions with two ARF1 binding proteins, neuronal calcium sensor-1 (NCS-1) and phosphatidylinositol-4 kinase-IIIbeta (PI4Kbeta).
Neuronal calcium sensor-1 and phosphatidylinositol 4-kinase beta stimulate extracellular signal-regulated kinase 1/2 signaling by accelerating recycling through the endocytic recycling compartment.
Sagi-Eisenberg et al., Tel Aviv-Yafo, Israel. In Mol Biol Cell, 2006
We further show that by activating phosphatidylinositol 4-kinase beta (PI4Kbeta) and increasing the cellular level of phosphatidylinositol(4) phosphate, neuronal calcium sensor-1 (NCS-1), a calmodulin-related protein, stimulates recycling and thereby enhances Fc epsilonRI-triggered activation and nuclear translocation of ERK1/2.
Functional implication of neuronal calcium sensor-1 and phosphoinositol 4-kinase-beta interaction in regulated exocytosis of PC12 cells.
Vitale et al., Strasbourg, France. In J Biol Chem, 2006
functional implication of a NCS-1.PI4K-beta complex in regulated exocytosis in neurons
Subcellular localization and structural function of endogenous phosphorylated phosphatidylinositol 4-kinase (PI4K92).
Heilmeyer et al., Bochum, Germany. In J Biol Chem, 2006
Anti-phosphopeptide antibodies were raised against phosphatidylinositol 4-kinase (PI4K92) phosphorylation sites (Suer, S., Sickmann, A., Meyer, H. E., Herberg, F. W., and Heilmeyer, L. M. Jr. (2001) Eur.
Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases.
Weisz et al., Pittsburgh, United States. In J Biol Chem, 2005
PI4KIIIbeta (PIK4CB) and PI4KIIalpha (PIK4CA) localize to discrete subcompartments of the Golgi complex in Madin-Darby canine kidney (MDCK) cells.
Phosphatidylinositol 4-kinasebeta is critical for functional association of rab11 with the Golgi complex.
van Bergen en Henegouwen et al., Utrecht, Netherlands. In Mol Biol Cell, 2004
Phosphatidylinositol 4-kinasebeta (PI4Kbeta) plays an essential role in maintaining the structural integrity of the Golgi complex.
[Construction of middle fragment deletion mutant with improved gene splicing by overlap extension].
Xia et al., Changsha, China. In Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2004
OBJECTIVE: To construct a phosphatidylinositol 4-kinase beta (PI4K-beta) mutant with the 325th to 373rd amino acid codons deleted, and try to develop a simple method for constructing middle fragment deletion mutant.
Neuronal calcium sensor-1 and phosphatidylinositol 4-kinase beta regulate IgE receptor-triggered exocytosis in cultured mast cells.
Sagi-Eisenberg et al., Tel Aviv-Yafo, Israel. In J Immunol, 2003
Overexpression of a PI4K beta mutant in rat mast cells inhibits IgE receptor-triggered phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis and exocytosis.
Mammalian phosphatidylinositol 4-kinases.
Szivák et al., Bochum, Germany. In Iubmb Life, 2003
PI4K230 has been found in the nucleolus, PI4K92 in the nucleus, additionally further broadening the function of these enzymes.
Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase beta interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis.
Rosa et al., Milano, Italy. In J Cell Sci, 2002
NCS-1 protein and 1-phosphatidylinositol 4-kinase b interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis.
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