Growing roles for the mTOR pathwaymore suppliers
In Molecular Cancer, 2004
... 17-allyloamino-17-demethoxygeldanamycin (17-AAG) and gefitinib were obtained from LC Laboratories (Woburn, MA, USA) and PHA-665752 was from Tocris Biosciences (St ...
Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype.
Lausanne, Switzerland. In Pflugers Arch, Feb 2016
Germline loss-of-function mutations of the mineralocorticoid receptor (MR) in humans and in mice lead to the "renal" form of type 1 pseudohypoaldosteronism (PHA-1), a case of aldosterone resistance characterized by salt wasting, dehydration, failure to thrive, hyperkalemia, and metabolic acidosis.
In Science, Dec 2015
ERRATUM FOR THE REPORT "Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4" by H.-T. Hsu et al., Science 350, aad5928 (2015).
Structural Biology Insight for the Design of Sub-type Selective Aurora Kinase Inhibitors.
Pondicherry, India. In Curr Cancer Drug Targets, 2014
The majority of the inhibitors (VX-680/MK-0457, PHA-739358, CYC116, SNS-314, AMG 900, AT-9283, SCH- 1473759, ABT-348, PF-03814735, R-763/AS-703569, KW-2449 and TAK-901) are pan-selective (isoform non-selective) and few are Aurora A (MLN8054, MLN8237, VX-689/MK5108 and ENMD 2076) and Aurora B (AZD1152 and GSK1070916) sub-type selective.
Polyhydroxyalkanoates: Much More than Biodegradable Plastics.
More papers using
Buenos Aires, Argentina. In Adv Appl Microbiol, 2014
The cycle of PHA synthesis and degradation has been recognized as an important physiological feature when these biochemical pathways were originally described, yet its role in bacterial processes as diverse as global regulation and cell survival is just starting to be appreciated in full.
Pesticide Fact Sheet
In Genetics and Molecular Biology, 2000
... USA), 15% foetal calf serum, antibiotics (penicillin 250 U/mL and streptomycin 250 μg/mL), and phytohaemagglutinin (PHA, 180 μg/mL, Welcome, Dartford, England).Chromosome preparations were obtained by the standard cytogenetic method; 2 h before harvest, colchicine (Merck, Darmstadt, Germany) was added ...