GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Ets variant 3
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009] (from
Kurisawa et al., Singapore, Singapore. In Acta Biomater, Feb 2016
UNASSIGNED: A novel ternary nanogel based on the self-assembly of hyaluronic acid (HA)-(-)-epigallocatechin gallate (EGCG) conjugates, linear polyethylenimine (PEI) and Granzyme B (GzmB) in aqueous environment was developed for the targeted intracellular delivery of GzmB into cancer cells.
Neale et al., Sydney, Australia. In Pancreatology, Jan 2016
AIM: Because of increasing awareness of variations in the use of pancreatic exocrine replacement therapy, the Australasian Pancreatic Club decided it was timely to re-review the literature and create new Australasian guidelines for the management of pancreatic exocrine insufficiency (PEI).
Kim et al., Suwŏn, South Korea. In Stem Cells Int, Dec 2015
In this study, we applied hTMSCs to a nonviral gene delivery system using polyethyleneimine (PEI) as a gene carrier; furthermore, the cytotoxicity and transfection efficiency of hTMSCs were evaluated to confirm their potential as resources in gene therapy.
Polymeric nanocarriers, such as polyethylenimine (PEI), poly(L-lysine) (PLL), poly[2-(dimethylamino) ethyl methacrylate] (PDMAEMA), polyamidoamine (PAMAM), chitosan and poly(amino-co-ester)s (PAEs), play an important role in gene delivery.
Kwon, Irvine, United States. In Acc Chem Res, 2012
Tailoring the ketalization ratio and the molecular weight of ketalized branched PEI (K-BPEI) offers molecular control of the intracellular trafficking of siRNA/polymer polyplexes and, therefore, the gene silencing efficiency.
Schubert et al., Jena, Germany. In Chem Soc Rev, 2012
The contemporary strategies towards linear and branched poly(ethylene imine)s with modified surface characteristics, PEI-based copolymers as well as conjugates with bioactive molecules will be discussed.
Anderson et al., Cambridge, United States. In Acc Chem Res, 2008
These polymers are more effective for gene delivery than top commercially available nonviral vectors including jet-PEI and Lipofectamine 2000 and are comparable to adenovirus for in vitro gene delivery to human primary cells.