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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

IKAROS family zinc finger 5

Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Pegasus, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002] (from NCBI)
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Top mentioned proteins: HAD, CAN, TIMI, fibrillin-1, ACID
Papers on Pegasus
Safety and efficacy of Sclerocarya birrea (A.Rich.) Hochst (Marula) oil: A clinical perspective.
Viljoen et al., Pretoria, South Africa. In J Ethnopharmacol, Jan 2016
METHODS AND MATERIALS: Quantification of the fatty acid methyl esters (FAMEs) was done using a LECO Pegasus 4D GC×GC-MS.
Long-Term Use of Ticagrelor in Patients with Prior Heart Attack: Ticagrelor Plus Aspirin Versus Aspirin Monotherapy.
Mazzoni et al., Wilmington, United States. In Postgrad Med, Jan 2016
Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial.
Ticagrelor shift from PLATO to PEGASUS: Vanished mortality benefit, excess cancer deaths, massive discontinuations, and overshooting target events.
Serebruany, Baltimore, United States. In Int J Cardiol, Jan 2016
After the successful PLATO, failed both PHILO and ATLANTIC, PEGASUS trial assessed efficacy and safety of ticagrelor (120 mg/day and 180 mg/day) on top of aspirin versus aspirin alone beyond 1 year in patients with stable coronary disease.
Clopidogrel, prasugrel, ticagrelor or vorapaxar in patients with renal impairment: do we have a winner?
Kim et al., Towson, United States. In Expert Rev Cardiovasc Ther, Dec 2015
The authors summarize available FDA-confirmed evidence from the latest trials with approved antiplatelet agents, namely clopidogrel (CAPRIE, CURE, CREDO, CLARITY, CHARISMA); prasugrel (TRITON, TRILOGY); ticagrelor (PLATO, and PEGASUS); and vorapaxar (TRACER and TRA2P) in RI patient cohorts on top of aspirin as part of dual antiplatelet therapy (DAPT).
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
Kim et al., Towson, United States. In Thromb Haemost, Dec 2015
Later, extra cancer deaths reported following clopidogrel and prasugrel in DAPT, and after ticagrelor in PEGASUS are also of concern.
Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12 inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54.
Sabatine et al., Boston, United States. In Eur Heart J, Nov 2015
AIMS: Ticagrelor reduced major adverse cardiovascular event (MACE) by 15-16% in patients with prior myocardial infarction (MI) in PEGASUS-TIMI 54.
Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial.
Bonaca et al., Boston, United States. In Eur Heart J, Nov 2015
METHODS AND RESULTS: Patients with a history of MI 1-3 years prior from PEGASUS-TIMI 54 were stratified based on estimated glomerular filtration rate (eGFR), with <60 mL/min/1.73
Survival After Solid Cancers in Antithrombotic Trials.
Kim et al., Praha, Czech Republic. In Am J Cardiol, Oct 2015
The impact of antithrombotics on cancer is currently under intense investigation because of the excess of solid cancers in trials after thienopyridines such as TRITON (prasugrel), DAPT (prasugrel and clopidogrel), PAR-1 thrombin antagonist in TRACER (vorapaxar), pyrimidines in PEGASUS (ticagrelor), and in APPRAISE-2 after apixaban.
Configuration of watermelon fruit quality in response to rootstock-mediated harvest maturity and postharvest storage.
Gerasopoulos et al., Nicosia, Cyprus. In J Sci Food Agric, Aug 2015
Pegasus, cultivated as scion on interspecific hybrid squash rootstock TZ148 and as non-grafted control, was stored at 25 °C following sequential harvests from the onset of ripening to over-maturity.
Long-term outcomes in high-risk patients with non-ST-segment elevation myocardial infarction.
Cohen, Newark, United States. In J Thromb Thrombolysis, Jun 2015
A recent subgroup analysis from the DAPT study in patients with or without MI who had undergone coronary stenting (31 % presented with MI; 53 % had NSTEMI) and the prospective PEGASUS-TIMI 54 trial in patients with a prior MI and at least one other risk factor (40 % had NSTEMI) demonstrated that long-term dual antiplatelet therapy improved cardiovascular outcomes but increased bleeding.
Long-term use of ticagrelor in patients with prior myocardial infarction.
PEGASUS-TIMI 54 Steering Committee and Investigators et al., Macao. In N Engl J Med, Jun 2015
(Funded by AstraZeneca; PEGASUS-TIMI 54
Prevalence of Mental Disorders in the South-East of Spain, One of the European Regions Most Affected by the Economic Crisis: The Cross-Sectional PEGASUS-Murcia Project.
Alonso et al., Murcia, Spain. In Plos One, 2014
METHODS AND FINDINGS: The PEGASUS-Murcia Project is a cross-sectional face-to-face interview survey of a representative sample of non-institutionalized adults in Murcia administered between June 2010 and May 2012.
Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial.
Sabatine et al., Paris, France. In Am Heart J, 2014
STUDY DESIGN: PEGASUS-TIMI 54 is a randomized, double-blind, placebo-controlled, multinational clinical trial designed to evaluate the efficacy and safety of ticagrelor in addition to aspirin (75-150 mg) for the prevention of major adverse cardiovascular events in patients with a history of myocardial infarction and risk factors.
Genetically modified animals from life-science, socio-economic and ethical perspectives: examining issues in an EU policy context.
Salter et al., Newcastle upon Tyne, United Kingdom. In N Biotechnol, 2013
The interdisciplinary EC consortium (the PEGASUS project) aimed to examine the issues raised by the development, implementation and commercialisation of genetically modified (GM) animals, and derivative foods and pharmaceutical products.
Florida current: low-frequency variability as observed with moored current meters during april 1982 to june 1983.
Zantopp et al., In Science, 1985
The transport estimates, determined on the basis of constant shear extrapolation of the subsurface velocities to the surface, are in good agreement with transports derived from submarine cable and Pegasus measurements.
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