Proteomics of vitreous in neovascular age-related macular degeneration.
Heidelberg, Germany. In Exp Eye Res, Feb 2016
Using a stringent statistical analysis with implementation of the closed test principle, we were able to identify four proteins that may be involved in the pathophysiology of nAMD: Clusterin, opticin, pigment epithelium-derived factor and prostaglandin-H2 d-isomerase.
PEDF in diabetic retinopathy: a protective effect of oxidative stress.
Shanghai, China. In J Biomed Biotechnol, 2011
This paper highlights the current understanding of probable mechanism of how PEDF blocks deterioration of diabetic retinopathy through its antioxidative properties and application prospects of PEDF as a novel therapeutic target in diabetic retinopathy.