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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


PCM, Icmt, PIMT, isoprenylcysteine carboxyl methyltransferase, PCMT1, SEREX-defined, Tgs1
catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, ACID, HAD, V1a, OUT
Papers on PCM
Diatom Vacuolar 1,6-β-transglycosylases can Functionally Complement the Respective Yeast Mutants.
Kroth et al., Konstanz, Germany. In J Eukaryot Microbiol, Feb 2016
Furthermore, we demonstrated the functionality of the diatom enzymes by expressing TGS1 and 2 proteins in yeast which resulted in a partial complementation of growth deficiencies of a transglycosylase-deficient ∆kre6 yeast strain.
Paracoccidioides brasiliensis interacts with dermal dendritic cells and keratinocytes in human skin and oral mucosa lesions.
Sotto et al., São Paulo, Brazil. In Med Mycol, Feb 2016
UNASSIGNED: Paracoccidioidomycosis (PCM) is a systemic disease caused by the fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii.
Aging Stem Cells Lose the Capability to Distribute Damaged Proteins Asymmetrically.
Larrick et al., Sunnyvale, United States. In Rejuvenation Res, Dec 2015
Moreover, the detrimental changes associated with progerin expression in HGPS are partially reversible experimentally after treatment with statins, a farnesyltransferase inhibitor, a isoprenylcysteine carboxyl methyltransferase inhibitor, or sulforaphane.
A new revisional surgery for severe protein-calorie malnutrition after Roux-en-Y gastric bypass: successful duodenojejunal reconstruction using jejunal interposition.
Marchini et al., Ribeirão Preto, Brazil. In Surg Obes Relat Dis, Oct 2015
UNASSIGNED: Roux-en-Y gastric bypass (RYGB) may result in nutritional deficiencies, mainly involving micronutrients, and occasionally protein-calorie malnutrition (PCM) because of the resulting anatomic and functional changes.
ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole.
Liu et al., Spokane, United States. In Cell, Aug 2015
Although it is known that the centrioles play instructive roles in pericentriolar material (PCM) assembly and that the PCM is essential for proper centriole formation, the mechanism that governs centriole-PCM interaction is poorly understood.
Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro.
Hyman et al., Dresden, Germany. In Science, Jun 2015
The centrosome organizes microtubule arrays within animal cells and comprises two centrioles surrounded by an amorphous protein mass called the pericentriolar material (PCM).
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.
Pagano et al., New York City, United States. In Nat Cell Biol, 2015
We also found that Cep68 forms a complex with Cep215 (also known as Cdk5Rap2) and PCNT (also known as pericentrin), two PCM (pericentriolar material) proteins involved in centriole engagement.
Cytogenetic Study and Analysis of Protein Expression in Plasma Cell Myeloma with t(11;14)(q13;q32): Absence of BCL6 and SOX11, and Infrequent Expression of CD20 and PAX5.
Miura et al., In J Clin Exp Hematop, 2014
The t(11;14)(q13;q32) translocation is the most common chromosomal translocation in plasma cell myeloma (PCM), but the cytogenetic and immunophenotypic features of PCM with t(11;14)(q13;q32) remain to be fully elucidated.
CD200 Expression on Plasma Cell Myeloma Cells is Associated with the Efficacies of Bortezomib, Lenalidomide and Thalidomide.
Takimoto et al., In J Clin Exp Hematop, 2014
Plasma cell myeloma (PCM) is a devastating disease with a highly heterogeneous outcome, with survival ranging from a few months to longer than 10 years.
Paracoccidioides-host Interaction: An Overview on Recent Advances in the Paracoccidioidomycosis.
Mendes-Giannini et al., São Paulo, Brazil. In Front Microbiol, 2014
Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis (PCM), an important endemic mycosis in Latin America.
Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions.
Alzahrani et al., Riyadh, Saudi Arabia. In Adv Hematol, 2014
PBL remains a diagnostic challenge due to its peculiar morphology and an immunohistochemical profile similar to plasma cell myeloma (PCM).
α-Glucosidase activity of oleanolic acid and its oxidative metabolites: DFT and Docking studies.
Shah et al., Kuala Selangor, Malaysia. In Mini Rev Med Chem, 2014
To elucidate the inhibitory mechanism of compounds 1, 2 and 3 against α-glucosidase, we calculated (i) their electronic and optical properties using DFT and TD-DFT at the B3LYP/6-31G(d) level in gas and IEF-PCM solvent; and (ii) their binding energies to α-glucosidase via docking study.
Towards predictive resistance models for agrochemicals by combining chemical and protein similarity via proteochemometric modelling.
Overington et al., Cambridge, United Kingdom. In J Chem Biol, 2014
As summarized in this opinion article, a technique termed 'proteochemometric modelling' (PCM), from the field of chemoinformatics, could aid in the quantification and prediction of resistance that acts via point mutations in the target proteins of an agent.
Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
Bergo et al., Göteborg, Sweden. In Science, 2013
Here, we found that a hypomorphic allele of isoprenylcysteine carboxyl methyltransferase (ICMT) increased body weight, normalized grip strength, and prevented bone fractures and death in Zmpste24-deficient mice.
Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts.
Gonzalez et al., Barcelona, Spain. In Nat Cell Biol, 2013
During interphase in Drosophila neuroblasts, the Centrobin (CNB)-positive daughter centriole retains pericentriolar material (PCM) and organizes an aster that is a key determinant of the orientation of cell division.
Maternal PCMT1 gene polymorphisms and the risk of neural tube defects in a Chinese population of Lvliang high-risk area.
Zhang et al., Beijing, China. In Gene, 2012
The results implied that maternal polymorphisms in PCMT1 might be a potential genetic risk factor for isolated anencephaly in the Chinese population of Lvliang.
Requirement of protein l-isoaspartyl O-methyltransferase for transcriptional activation of trefoil factor 1 (TFF1) gene by estrogen receptor alpha.
Han et al., South Korea. In Biochem Biophys Res Commun, 2012
PIMT may act as a co-activator in ERalpha-mediated transcription of TFF1 through its recruitment to the promoter via interacting with ERalpha.
The microRNA 15a/16-1 cluster down-regulates protein repair isoaspartyl methyltransferase in hepatoma cells: implications for apoptosis regulation.
Ingrosso et al., Napoli, Italy. In J Biol Chem, 2012
Control of PCMT1 expression by microRNA 15a/16-1 may thus represent a late checkpoint in apoptosis regulation
Protein L-isoaspartyl methyltransferase regulates p53 activity.
Han et al., Suwŏn, South Korea. In Nat Commun, 2011
Study provides new insight into the molecular mechanisms by which PIMT suppresses the p53 activity through carboxyl methylation, and suggests a therapeutic target for cancers.
Cross-regulation between protein L-isoaspartyl O-methyltransferase and ERK in epithelial mesenchymal transition of MDA-MB-231 cells.
Cho et al., Suwŏn, South Korea. In Acta Pharmacol Sin, 2011
A tight cross-regulation exists between ERK and PIMT in regards to their activation and expression during the epithelial mesenchymal transition.
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