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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Membrane protein, palmitoylated 6

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: MPP, V1a, CAN, PrP, ACID
Papers using PALS2 antibodies
Mouse embryo fibroblasts lacking the tumor suppressor menin show altered expression of extracellular matrix protein genes.
Laudet Vincent, In PLoS ONE, 2006
... ICI 182780 and the ERα specific antagonist 4,4′,4″-(4-Propyl-[1H] pyrazole-1,3,5-triyl) trisphenol (MPP), were purchased from Tocris (Ellisville, MO) ...
The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost
Margolis Ben et al., In The Journal of Cell Biology, 1994
... Pals1 L27N domain was removed from the chimeric construct via the Pme1 sites, and the Pals2 L27N domain was reinserted.Human kidney Quickclone cDNA (CLONTECH Laboratories, Inc.) was used ...
Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources
Schmidt Ulrike, In PLoS ONE, 1976
... separate experiments, cells were pre-treated with i) 10 mM NAC for 2 h; ii) 100 nM MPP ERα antagonist (Tocris Cookson, Ellisville, MO) for ...
Papers on PALS2
Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.
Nijnik et al., Montréal, Canada. In Cell Death Differ, Feb 2016
Specifically, Mysm1(-/-)Puma(-/-) mice show full rescue of multipotent progenitor (MPP) viability, partial rescue of HSC quiescence and function, but persistent lymphopenia.
Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson's disease.
Hu et al., Nanjing, China. In Neuroscience, Feb 2016
Similarly, AQP4 deficiency augmented the activation of NF-κB pathway and the production of IL-1β and TNF-α in midbrain astrocyte cultures treated with MPP(+) (1-methyl-4-phenylpyridinium).
Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease.
Fournier et al., Mont-Saint-Aignan, France. In Biochim Biophys Acta, Feb 2016
Hence, we explored the putative autophagy-modulating properties of PACAP in in vitro and in vivo models of PD, using the neurotoxic agents 1-methyl-4-phenylpyridinium (MPP(+)) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), respectively, to trigger alterations of DA neurons.
The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells.
Wu et al., Shanghai, China. In Biochem Biophys Res Commun, Feb 2016
PD cell models were established by using methyl-4-phenylpyridinium(MPP(+)), which induced inhibition of cell proliferation, cell cycle arrest and apoptosis.
Clinical impacts of a micropapillary pattern in lung adenocarcinoma: a review.
Yuan et al., Hangzhou, China. In Onco Targets Ther, Dec 2015
Micropapillary-predominant adenocarcinoma (MPA), which is defined by micropapillary pattern (MPP), is the primary histological pattern observed semiquantitatively in 5% increments on resection specimens, and MPA was formally determined to be a new histological subtype according to the new multidisciplinary classification in 2011.
Involvement of membrane skeletal molecules in the Schmidt-Lanterman incisure in Schwann cells.
Ohno et al., Matsumoto, Japan. In Med Mol Morphol, Dec 2015
4.1R-MPP (membrane palmitoylated protein) 1-glycophorin C is one of the basic molecular complexes of the membrane skeleton.
Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.
Goukassian et al., Boston, United States. In Front Oncol, 2014
We report here that low-dose (1)H- and (56)Fe-IR significantly decreased the hematopoietic early and late multipotent progenitor (E- and L-MPP, respectively) cell numbers in mouse BM over a period of up to 10 months after exposure.
Versatility of stem and progenitor cells and the instructive actions of cytokines on hematopoiesis.
Rolink et al., Birmingham, United Kingdom. In Crit Rev Clin Lab Sci, 2014
For many years, developing hematopoietic cells have been strictly compartmentalized into a rare population of multi-potent self-renewing hematopoietic stem cells (HSC), multi-potent hematopoietic progenitor cells (MPP) that are undergoing commitment to particular lineage fates, and recognizable precursor cells that mature towards functional blood and immune cells.
Green Tea Catechin, EGCG, Suppresses PCB 102-Induced Proliferation in Estrogen-Sensitive Breast Cancer Cells.
Bauer et al., Indianapolis, United States. In Int J Breast Cancer, 2014
Furthermore, the proliferative effects of PCB 102 were mediated by ERα and could be abrogated by the selective ERα antagonist MPP.
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Trumpp et al., Heidelberg, Germany. In Cell Stem Cell, 2014
In this study, we present integrated quantitative proteome, transcriptome, and methylome analyses of hematopoietic stem cells (HSCs) and four multipotent progenitor (MPP) populations.
Melanin affinity and its possible role in neurodegeneration.
Lindquist et al., Uppsala, Sweden. In J Neural Transm, 2013
MPTP/MPP(+) that has been causally linked with Parkinsonism has high affinity for neuromelanin, and the induced dopaminergic denervation correlates with the neuromelanin content in the cells.
Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves.
Ohno et al., Japan. In Mol Cell Biol, 2012
In the mouse sciatic nerve, protein 4.1G colocalized at Schmidt-Lanterman incisures (SLI) and the paranodes with a member of the membrane-associated guanylate kinase (MAGUK) family, membrane protein palmitoylated 6.
Straight talk with...Ellen 't Hoen.
Mullard, In Nat Med, 2010
The initiative-called the Medicines Patent Pool (MPP)-aims to streamline licensing processes, drive the combination of multiple HIV medicines into one pill and foster the development of drug formulations for children.
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death.
Park et al., Ottawa, Canada. In Nat Cell Biol, 2010
Overexpression of Ape1(WT) and Ape1(T232A), but not the phosphorylation mimic Ape1(T232E), protects neurons against MPP(+)/MPTP.
IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses.
Artis et al., Philadelphia, United States. In Nature, 2010
Here we show that IL25, a member of the IL17 cytokine family, promotes the accumulation of a lineage-negative (Lin(-)) multipotent progenitor (MPP) cell population in the gut-associated lymphoid tissue that promotes T(H)2 cytokine responses.
Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.
Meisinger et al., Freiburg, Germany. In Cell, 2009
The N-termini of the mature proteins and thus peptidase cleavage sites have only been determined for a small fraction of mitochondrial proteins and yielded a controversial situation for the cleavage site specificity of the major mitochondrial processing peptidase (MPP).
MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation.
Pruijn et al., Nijmegen, Netherlands. In Nucleic Acids Res, 2004
MPP6 is a nucleolus-specific exosome co-factor required for its role in the maturation of 5.8S rRNA.
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.
Karin et al., San Diego, United States. In Cell, 2001
MPP6 was found to be associated with the exosome, a multiprotein complex involved in RNA degradation.
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