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Exosome component 8

p9, Rrp43p, Rrp43, OIP2
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2009] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, p15, MHC
Papers using p9 antibodies
BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction
Schmitz Jürgen et al., In The Journal of Experimental Medicine, 1999
... CD19 (mAb 4G7, IgG1; Becton Dickinson), CD56 (mAb MY31, IgG1; Becton Dickinson), and CD14 (mAb MφP9, IgG2b; Becton Dickinson), respectively ...
Papers on p9
N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.
Kappler et al., Aurora, United States. In Proc Natl Acad Sci U S A, Nov 2015
Mimotope peptides with much higher activity share a C-terminal motif, WXRM(D/E), that is predicted to lie in the p5 to p9 position in the mouse MHC class II, IA(g7) binding groove.
P2 of Rice grassy stunt virus (RGSV) and p6 and p9 of Rice ragged stunt virus (RRSV) isolates from Vietnam exert suppressor activity on the RNA silencing pathway.
Brugidou et al., Montpellier, France. In Virus Genes, Oct 2015
In addition, we identified two new silencing suppressors that displayed mild activity: p2 of RGSV and p9 of RRSV.
Peptide ligand structure and I-Aq binding avidity influence T cell signaling pathway utilization.
Kang et al., Memphis, United States. In Clin Immunol, Oct 2015
To answer this question we developed a panel of peptides designed so that amino acids interacting with the p6 and p9 predicted MHC binding pockets were altered.
Interaction research on the antiviral molecule dufulin targeting on southern rice black streaked dwarf virus p9-1 nonstructural protein.
Song et al., Guiyang, China. In Viruses, Mar 2015
This study found dufulin (DFL), an ideal anti-SRBSDV molecule, and investigated the interactions of DFL targeting on the nonstructural protein P9-1.
17β-estradiol ameliorates oxygen-induced retinopathy in the early hyperoxic phase.
Li et al., Xi'an, China. In Biochem Biophys Res Commun, Mar 2015
We found that large central capillary-free areas were induced in the retinas of pups exposed to hyperoxia on postnatal day 9 (P9), whereas vascularization was almost complete in the retinas of pups exposed to normoxia at the same age.
Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses.
Mahieux et al., Lyon, France. In J Virol, Feb 2015
The p9 localization is similar to that of HTLV-1 p12 and induced a strong decrease in the calreticulin signal, similarly to HTLV-1 p12.
Development of the First Cisgenic Apple with Increased Resistance to Fire Blight.
Broggini et al., Zürich, Switzerland. In Plos One, 2014
A cisgenic apple line C44.4.146 was regenerated using the cisgene FB_MR5 from wild apple Malus ×robusta 5 (Mr5), and the previously established method involving A. tumefaciens-mediated transformation of the fire blight susceptible cultivar 'Gala Galaxy' using the binary vector p9-Dao-FLPi.
The selection performance of an antibody library displayed on filamentous phage coat proteins p9, p3 and truncated p3.
Lamminmäki et al., Turku, Finland. In Bmc Res Notes, 2013
Several capsid proteins have been applied for displaying antibodies, of which gene III (p3) protein is used the most followed by experiments with gene IX (p9) protein.
Activation of the RNA-dependent protein kinase (PKR) of lymphocytes by regulatory RNAs: implications for immunomodulation in HIV infection.
De Lucca et al., Ribeirão Preto, Brazil. In Curr Hiv Res, 2005
Special emphasis will be placed on a regulatory RNA, named p9-RNA, isolated from lymphocytes of animals immunized with the synthetic peptide p9 (pol: 476-484) of HIV-1.
The protein network of HIV budding.
Sundquist et al., Salt Lake City, United States. In Cell, 2003
AIP1 also binds the HIV-1 p6(Gag) and EIAV p9(Gag) proteins, indicating that it can function directly in virus budding.
AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.
Göttlinger et al., Boston, United States. In Cell, 2003
AIP1 also binds to the L domain in EIAV p9, and this binding correlates perfectly with L domain function.
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
Pruijn et al., Nijmegen, Netherlands. In J Mol Biol, 2002
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity.
Altman et al., New Haven, United States. In Proc Natl Acad Sci U S A, 2002
A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity.
Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer.
Lippman et al., Houston, United States. In J Clin Oncol, 2002
The growth inhibition, cell-cycle, and apoptosis activity of these agents was evaluated in two skin SCC cell lines (SRB1-m7 and SRB12-p9).
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.
Tollervey et al., Heidelberg, Germany. In Cell, 1997
We identified a complex in S. cerevisiae, the "exosome," consisting of the five essential proteins Rrp4p, Rrp41p, Rrp42p, Rrp43p, and Rrp44p (Dis3p).
Morphogenesis of human immunodeficiency virus type 1.
Khan et al., Birmingham, United States. In Pathobiology, 1991
The two nucleic-acid-binding proteins p7 and p9 are synthesized from p15 by proteolytic cleavage.
A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10.
Kruseman et al., In Nature, 1987
Simpson et al. recently reported preliminary evidence for linkage between the DNA probe p9-12A on chromosome 10 and MEN2A.
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