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Zinc finger protein 398

This gene encodes a member of the Kruppel family of C2H2-type zinc-finger transcription factor proteins. The encoded protein acts as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described, but their full length sequence has not been determined. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, p75, p69, p63
Papers on p71
Foamy virus Gag p71-p68 cleavage is required for template switch of the reverse transcriptase.
Bodem et al., W├╝rzburg, Germany. In J Virol, 2013
In contrast to orthoretroviruses, processing of foamy viral p71 Gag is limited to a single cleavage site.
Orthoretroviral-like prototype foamy virus Gag-Pol expression is compatible with viral replication.
Lindemann et al., Dresden, Germany. In Retrovirology, 2010
PFV Gag-Pol precursor fusion proteins with inactivated protease were highly deficient in regular particle release, although coexpression of p71(Gag) resulted in a significant copackaging of these proteins.
[Polymorphism in the human 2'-5'-oligoadenylate synthetase genes (OAS), associated with predisposition to severe forms of tick-borne encephalitis, in populations from North Eurasia].
Voevoda et al., In Mol Biol (mosk), 2010
In current study we investigated the distribution of three of that SNPs (OAS3rs2285932 (C/T Ile438Ile), OAS3rs2072136 (G/A, Ser567Ser) and OAS2 rs15895 (G/A, Trp720Ter relative to p71 isoform)) in seven populations from North Eurasia: Caucasians (Russians and Germans (from Altai region)), Central Asian Mongoloids (Altaians, Khakasses, Tuvinians and Shorians) and Arctic Mongoloids (Chukchi).
Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection.
Lin et al., Taipei, Taiwan. In J Immunol, 2010
Four genes, OAS1, OAS2, OAS3, and OAS-like (OASL), have been identified in the human OAS gene family, and 10 isoforms, including OAS1 (p42, p44, p46, p48, and p52), OAS2 (p69 and p71), OAS3 (p100), and OASL (p30 and p59) can be generated by alternative splicing.
Promiscuous peptides on the nontypeable Haemophilus influenzae P6 outer membrane protein.
Harabuchi et al., Asahikawa, Japan. In J Clin Immunol, 2008
To develop a vaccine formulation effective in the general population, we identified promiscuous T cell epitope peptides (p41-55, p71-85) on P6.
Correct capsid assembly mediated by a conserved YXXLGL motif in prototype foamy virus Gag is essential for infectivity and reverse transcription of the viral genome.
Lindemann et al., Dresden, Germany. In J Virol, 2007
Unlike other retrovirus Gag proteins, the prototype foamy virus (PFV) p71(g)(ag) protein is not processed into mature matrix (MA), capsid (CA), and nucleocapsid (NC) subunits.
Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine.
Poirier et al., Bethesda, United States. In Environ Mol Mutagen, 2007
mtDNA quantity was increased at p5 and p11, and 65% depleted at p71.
Expression of the adaptor protein m-Numb in mouse male germ cells.
Vicini et al., Roma, Italy. In Reproduction, 2006
By reverse transcriptase-PCR and western blot analyses, we further identify p71 as the predominantly expressed isoform in germ cells.
Expression of ZER6 in ERalpha-positive breast cancer.
Weigel et al., Philadelphia, United States. In J Surg Res, 2005
BACKGROUND: ZER6 is a C2H2 zinc finger transcription factor with two isoforms (p52-ZER6 and p71-ZER6), which are differentially repressed by a ligand-dependent interaction with estrogen receptor-alpha (ERalpha).
Identification of human T cell epitopes in Japanese cypress pollen allergen, Cha o 1, elucidates the intrinsic mechanism of cross-allergenicity between Cha o 1 and Cry j 1, the major allergen of Japanese cedar pollen, at the T cell level.
Kino et al., Saitama, Japan. In Clin Exp Allergy, 2005
While four T cell epitopes, p11-30, p211-230, p251-270 and p331-350, were common to Cha o 1 and Cry j 1, 4 T cell epitopes, p61-80, p71-90, p311-330 and p321-340, were considered to be unique to Cha o 1.
Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity.
Baker et al., Atlanta, United States. In J Virol, 2004
In contrast, processing at the nsp2/3 site is less efficient, since a approximately 300-kDa intermediate (NSP2-3) is detected, but ultimately nsp2 (p71) and nsp3 (p213) are generated.
Identification of peptides containing T-cell epitopes of Japanese cedar (Cryptomeria japonica) pollen allergen (Cry j 1) in dogs.
Tsujimoto et al., Tokyo, Japan. In Vet Immunol Immunopathol, 2004
Three reactive peptides were identical in a relatively high population of experimental dogs, which were Nos. 8 (p71-90) (41%), 10 (p91-110) (50%), and 11 (p101-120) (41%).
A CD8 DE loop peptide analog prevents graft-versus-host disease in a multiple minor histocompatibility antigen-mismatched bone marrow transplantation model.
Korngold et al., Philadelphia, United States. In Biol Blood Marrow Transplant, 2004
The DE loop (p71-78) was identified as such a target region, and a panel of synthetic cyclized peptide mimics of this region were tested for their inhibitory effects on cytotoxic T lymphocyte activity in human cell-mediated lympholysis assays.
Impact of deletions within the Bam HI-L fragment of attenuated Marek's disease virus on vIL-8 expression and the newly identified transcript of open reading frame LORF4.
Schat et al., Ithaca, United States. In Virus Genes, 2003
Within the putative vIL-8 gene promoter sequence, there was little difference among the non-attenuated strains; however significant deletions were identified in the attenuated JM-16/p71, Md11 (R2/23), and 584Ap80C strains.
Drosophila sec10 is required for hormone secretion but not general exocytosis or neurotransmission.
Broadie et al., Nashville, United States. In Traffic, 2002
dSec10 has no detectable role in most forms of polarized trafficking/exocytosis, including neurotransmission, but rather is essential for endocrine secretion
Quantitative analysis of p40/p46 and p69/p71 forms of 2',5'-oligoadenylate synthetase mRNA by competitive PCR and its clinical application.
Tsuji et al., Okayama, Japan. In Clin Chem, 2002
We measured distinct forms of 2-5AS mRNA to analyze the relationship with its enzymatic activity and response to IFN therapy in chronic hepatitis C. METHODS: We established a method to quantify p40/p46 and p69/p71 forms of 2-5AS mRNA by use of reverse transcription followed by competitive PCR.
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